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Topimax (Topiramate)

Topimax is a medication that works in the brain and is sometimes used in patients with bipolar disorder (also known as manic depression). It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults. Bipolar disorder involves episodes of depression and/or mania.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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The present studies sought to identify the neural substrates underlying this potent pain inhibition by examining the effects of decerebration, spinalization and bilateral dorsolateral funiculus (DLF) lesions on vaginal stimulation-produced analgesia (VSPA). As they care for patients, physicians raise questions, but they pursue only a portion of them. These data indicate that extracellular zinc has a dual effect on I(CaT), blocking it acutely while causing its long-term upregulation. A canine nephropathy resembling minimal change nephrotic syndrome in man. More generally, the approach provides insights into both evolutionary processes and ecological costs and benefits of different plant growth strategies.

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Attrition in the RAND Health Insurance Experiment: a response to Nyman. Computed tomographic scans were obtained from 19 men with long histories of heavy marijuana smoking and who were also observed to smoke large amounts of marijuana under research ward conditions. Induction of apoptosis was dose dependent: 52 percent of the PBMCs exhibited Annexin V positivity after incubation with ATG at a dose of 500 microg/ml for 6 h, and 37 percent of the PBMCs exhibited DNA fragmentation after incubation with ATG at a dose of 1000 microg/ml for 24 h as demonstrated by TUNEL assay. The best results were obtained by the use of NSO as fusion line with taurine-supported media. Three oligopeptides were synthesized based on predicted MAGE-1 amino acid sequences and were used to generate rabbit anti-peptide anti-sera.

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We detected certain beliefs, attitudes, values, expectations and behaviour among the patients that were potentially useful for future primary prevention programmes on depression. In this report we show that NK cell inhibitory receptor Ly49A engagement on T cells dramatically limits T-cell activation and the resultant lymphoproliferative disorder that occurs in CTLA-4-deficient mice.

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Bacillus subtilis produces and exports a peptide sporulation killing factor (SkfA) that induces lysis of sibling cells. Cmax versus AUC relationships were established for all drugs and were amenable for limited sampling strategy for AUC prediction. Metabolic changes and problems of resuscitation in hypertrophic pyloric stenosis Morphological measurements known to characterize and discriminate the species in the samples such as junction thickness, branch thickness, terminal thickness, branch length, branch angle, and terminal spacing are then quantified.

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Detailed discussions are made on each type of volvulus, the etiology, pathogenesis, pathological anatomy, while particular extensions is given to the description of the results obtained that are compared with the data found from the examination of the literature. We report a case of a malignant right free wall AP that showed very rapid conduction during atrial fibrillation. Patients were followed up for one year, and all-cause mortality and re-admission data were analyzed.

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Pharmacological activation of kappa opioid receptors: aversive effects in adolescent and adult male rats. Injection of MVMp in tumor-bearing B6 mice resulted in viral gene expression in tumors and draining lymph nodes. Cloning and nucleotide sequence analyses of 11 genome segments of two American and one British equine rotavirus strains.

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The melanocytoma of the optic disc is a deeply-pigmented tumor located on the optic nerve head. This toolbox implements routines for blind source decomposition and connectivity estimation with the MVARICA approach. Stimulation of selected filaments of the nerve produced a response from the spindle that was attributed to intrafusal contraction.

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When children aged 0-4 years are analysed together as a group for poisoning risk, important differences for smaller age intervals by medicinal and non-medicinal substances are masked. Even if the vaccine is not clearly the cause of possible side effects, including possible allergic reactions occurring after vaccine administration, they should be reported to the appropriate authorized body. Here, we propose a structure model of the ORF3 protein consisting of four TM domains and forming a tetrameric assembly. The most important lesion components affecting retinal function were RPE elevation and subretinal tissue in OCT as well as neovascular membranes and haemorrhage in angiographies. While the input from the retina is topographic in the superficial layers, the deep layers project to the thalamic nucleus rotundus in a functional topographical manner.

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Isolation of Leptospira from wild forest animals in Amazonian Brazil. The first correlation assumed a possible relationship between the signal observed with the camera and Raman spectroscopy.

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Skin-transmitted pathogens and the heebie jeebies: evidence for a subclass of disgust stimuli that evoke a qualitatively unique emotional response. Spores pretreated with Oxone or hypochlorite were not sensitized to dry heat or freeze-drying.

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Our dataset consisted of 5,907 abstracts, representing work from 77 countries. Intravenous infusion of endotoxin (100 ng kg-1 over 30 min) significantly decreased the number of reticulorumen contractions.

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The relationship between serum adiponectin level and serum alanine aminotransferase elevation in Korean male with nonalcoholic fatty liver disease Confirmation of artemisinin-delayed parasite clearance in Plasmodium falciparum along the Thai-Myanmar border has inspired a global response to contain and monitor drug resistance to avert the disastrous consequences of a potential spread to Africa.

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Artemisone was 10 times more potent than artesunate in vitro against a panel of 12 P. Genome-wide association studies in adults have identified genetic loci associated with adiposity measures.

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Indeed, a high fat diet (HFD) increased plasma insulin levels associated with the impairment of insulin receptor signaling and the up-regulation of toll-like receptor 4 (TLR4) expressions. The effect of measles on streptomycin-sensitive tuberculous meningitis Almost all virus particles in the cytoplasm of satellite cells were contained in groups within vesicles and lysosome-like structures, suggesting that these glial cells may restrict the local diffusion of HEV. Antibodies from three of the epitope groups were able to detect the receptor by western blotting but did not inhibit G-CSF binding.

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The T allele of GIPR rs2287019 is associated with greater improvement of glucose homeostasis in individuals who choose a low-fat, high-carbohydrate, and high-fiber diet. Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes. Lobeline, like nicotine, has been found to significantly improve memory function as well as provide anxiolytic-like effects in the elevated plus maze. Therapeutic angiogenesis by bone marrow mononuclear cell transplantation: limitation in the elderly and augmentation by angiopoietin 1 gene therapy To investigate whether financial incentives could reverse the trend of declining interest in primary care specialties among U.S.

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Human metacarpal bone (MCP) bone was used as an example for demonstrating the applicability of the proposed method. Forensic discrimination of blue ballpoint pens on documents by laser ablation inductively coupled plasma mass spectrometry and multivariate analysis.

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Metastases including peritoneal dissemination and extensive lymph node involvement were absent so it was feasible to completely remove all of the macroscopic liver metastases. Screening and functional pathway analysis of genes associated with pediatric allergic asthma using a DNA microarray. The objective of this study is to develop a 3D ankle-foot model containing toe expression for designing an AFO (ankle-foot orthosis) with a training function. Seventy-one women, including 11 with twin pregnancies, who had uterine contractions and observed cervical changes. Mechanism(s) of the blood glucose lowering action of benfluorex.

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The strategy aims to integrate community-based health workers into the health system by creating a new group of workers, called community health assistants (CHAs). Urine erythrocyte morphology in patients with microscopic haematuria caused by a glomerulopathy. Mammalian gametogenesis provides a unique system in which to study cell-cycle regulation. Type II diabetes mellitus causes metabolic changes that may lead to early menopause and worsen climacteric symptoms. NhhA, Neisseriahia/hsf homologue, or GNA0992, is an oligomeric outer membrane protein of Neisseria meningitidis, recently included in the family of trimeric autotransporter adhesins.

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We analyzed AR using 2-way frequency tables and multivariable logistic regression. Locally advanced cervical cancers comprise a large majority of the gynecologic cancers in India and other developing countries. No differences were observed in prevalence of cognitive adverse events and depression between the two groups. Accurate segmentation of magnetic resonance (MR) images of the brain to differentiate features such as soft tissue, tumor, edema and necrosis is critical for both diagnosis and treatment purposes.

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Knowledge of the POLH status in skin tumours could contribute to an understanding of the role of this gene in the development of the most common cancer in the general population. Lesion vessels were defined as Type A, B, and C according to the standard of ACC/AHA in 1988. Disseminated intravascular coagulation with congestive heart failure and left ventricular thrombus: a case report with literature review of 7 cases.

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Electronic spectra of the protonated indole chromophore in the gas phase. There is no single comprehensive parameter for the identification of immunotoxic effects of mycotoxins, since immunological processes are very complex. In female rats, cyclic changes in the level of both binding activities were evident during the estrous cycle. For mothers with both GSTM1 and GSTT1 null genotype, both maternal and cord blood Hg levels were associated with lower birth weight.

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At the G0 stage the portion of simple and complex tetraploid cells was determined in the monkey kidney epithelium after the whole body 60Co gamma-irradiation, 620-660 R. Anesthetic management using auto-transfusion and hypothermia for massive bleeding Three days later, he achieved a complete recovery of his vision.

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Long non-coding RNAs (lncRNAs), a recently discovered class of non-coding genes, are transcribed throughout the genome. Seminomas and NSGCTs present significant differences in clinical features, therapy, and prognosis, and both show characteristics of the Primordial Germ Cells (PGCs).

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A total of 700 stool specimens were collected from children and assessed for the presence of rotaviruses by the dsRNA-PAGE technique. Our results suggest that clinical outcomes are not worsened using the conventional approach.

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A previous attempt of 24 h in the previous month was associated with the greatest difference in prediction. To investigate this, we simultaneously recorded brainstem and cortical electro-encephalographic activity while participants listened to periodic amplitude-modulated tones. A patient who initially presented with several episodes of transient monoparesis in the left leg was found to have severe stenosis of the right A2-A3 junction. Results suggest that condylar fractures in horses are pathologic fatigue or stress fractures that arise from a preexisting, branching array of cracks in the condylar groove of the distal end of MCIII or MTIII.

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Activation energy for the disproportionation of HBrO2 and estimated heats of formation of HBrO2 and BrO2. Thirty patients with focal leakage on angiography and serous retinal detachment or pigment epithelial detachment were designated as having acute CSR. The systematic review is a method of locating and evaluation of a synthesising evidence.

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Bivariate and multivariate associations between satisfaction with 32 elements of outpatient clinic in 6 domains (clinical preceptors, educational environment, ancillary staff, time management, administrative, personal experience) and likelihood of considering a GIM career. We developed a novel hydrogel system to promote the formation of TEC aggregates, based on the self-assembling property of the amphiphilic EAK16-II oligopeptides and its histidinylated analogue EAKIIH6.

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Ophthalmic artery Doppler velocimetric values in pregnant women at risk for preeclampsia. Effect of inhibiting endoxin by antidigoxin antiserum on myocardial ischemia/reperfusion injury in rats ALCAPA syndrome (anomalous origin of the left coronary artery from the pulmonary artery) is an exceedingly rare disease but lethal with clinical expression from myocardial infarction, congestive heart failure to death during early infancy and rare survival to adulthood. Tenosynovectomy, synovectomy, distal ulnar resection and transposition of the dorsal carpal ligament beneath the extensor tendons, has been effective in preventing rupture of the extensor tendons. Twenty-three patients had bilateral breast cancer (1,458 total breasts).

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Thrombocythemia with medullary megakaryocytosis and leukocytic hyperplasia The Y402H polymorphism within the seventh short consensus repeat of FH was recently shown to be associated with age-related macular degeneration, the most common cause of irreversible blindness in the Western world.

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These issues should be carefully addressed in the design and diffusion processes of an assistive robot. This article examines selected physiological, pathological and healthcare interventional changes with age that impact clinical drug studies and the decision to use drugs as therapy in older adults. Acquisition of cell identity in plants relies strongly on positional information, hence cell-cell communication and inductive signalling are instrumental for developmental patterning. Thirty minutes after completing cue exposure testing, participants were then evaluated for the acute effects of a smoked cigarette.

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Despite good reproducibility of individual in vitro assays, only the weight-of-evidence approach and results of multiple selected in vitro tests can allow for estimation of eye irritation hazard in vivo. Responses of rabbit cerebral cortex neurons in the early stages of defensive conditioning to a rhythmic light Proper treatment of nasal skin cancer, including nasal reconstruction, requires a structured multidisciplinary approach to achieve excellent tumor control and a satisfactory aesthetic and functional end result. The histopathologic study revealed squamous syringometaplasia of the dermal eccrine ducts. First-trimester medical abortion practices in Canada: National survey.

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Contribution of local area deprivation to cultural-linguistic inequalities in foetal growth restriction: trends over time in a Canadian metropolitan centre. Avoidant infants engaged in fewer active mother-oriented regulation behaviors than secure and resistant infants and engaged in more clindamycin hcl used to treat bv self-soothing in the mother involved condition than the mother uninvolved condition. The inter- and intra-observer variabilities were calculated for identical lesions and the overall response per case was determined. The replacement treatment with testosterone propionate in castrated rats blocked this effect. IL-32beta is present in tissues from humans, but is absent in rodents.

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Identification and characterization of onchoastacin, an astacin-like metalloproteinase from the simeprevir fda advisory committee filaria Onchocerca volvulus. Measuring integral P(exp) by dynamic air-pressure sensor makes it possible to estimate respiratory volume breath by breath, and the respiratory pressure-time integral waveform was useful in visually monitoring the respiration pattern. Because of its ability to aspirate clot and atheromatous material, TEC atherectomy may be useful in patients with stenoses in saphenous vein bypass grafts. The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling.

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The collected data were analyzed using statistical tests such as independent t-test, and Mann-Whitney and Chi-square tests. Magnetic resonance imaging scans were performed using a 1.5-tesla Philips scanner. klerimed clarithromycin 500mg treatment Lipid solubility of warfarin may contribute to warfarin resistance in patients receiving total parenteral nutrition.

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The Internet is an important source of health information for people with psychiatric conditions. It is of utmost importance to understand that evaluating PN as a routine practice in a simple way may also play a klabax tablets computers vitally important role in preventing foot ulcers or fall-related morbidity and mortality in adults with type 2 diabetes.

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Furthermore, the deimination of P1 Arg converts antithrombin risperidone 1 mg tabletten to a form with 4-fold higher affinity for the heparin pentasaccharide, similar to the affinity found for the P1 His variant, due to a lowered dissociation rate constant for the antithrombin-pentasaccharide complex. Hypothesis/Problem This study aimed to examine the accuracy of TTym for core body temperature assessment at emergency firefighting events compared with gastrointestinal temperature measurement (TGI) as measured by ingestible thermometers. Serotypes of Streptococcus pneumoniae isolated from blood cultures at Boston City Hospital between 1979 and 1982. Hemoglobin C after a red blood cell transfusion for sickle cell disease. Genes for the surface and core proteins were assigned to open reading frames 7 and 5/8.

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Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials. Ecology of aflatoxin producing prilosec prescription otc difference between then and than fungi and biocontrol of aflatoxin contamination. We evaluated the three-dimensional computed tomography (3D-CT) images of human faces using multidetector computed tomography (MDCT).

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Mechanism of potentiation of contraction in glycerol-treated muscles Current recommendations on timely DTP plavix clopidogrel 75 mg preis immunisation should be emphasised to prevent not only specific infectious diseases but also potentially SIDS.

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Operative details and postoperative outcomes were collected and evaluated. Conversely, smaller strains lead to fluconazole dosing for vaginal yeast infection localized and erratic irreversible particle rearrangements due to the motion of structural defects. MnTBAP increases BMPR-II expression in endothelial cells and attenuates vascular inflammation. One isoform is restricted to flowers, and is anchored to the cytosolic face of the endoplasmic reticulum membrane via a hydrophobic C-terminal transmembrane domain. A precise diagnosis of this venous anomaly is of great importance, since it needs to be differentiated from a central pulmonary artery, a pulmonary venous confluence, or an ascending vertical vein in totally anomalous pulmonary venous connection.