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Given the final model, plasma concentrations of paclitaxel seems to be relatively little affected by changes in metabolism or transport, while its main metabolite may be largely affected even by small changes. To evaluate the changes in mean macular thickness and volume and compare them with the mean thickness of the peripapillary nerve fiber layer in primary open angle glaucoma, using Time Domain (TD) optical coherence tomography ( OCT).

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Class IV-G (A/C) diffuse lupus nephritis and tubulointerstitial (TI) nephritis in a 31-year old woman was studied by light, immunofluorescence (IF), and electron microscopy (EM), to determine the pathogenesis of the TI lesions. The pharmacological cost of treatment for COPD patients seems to be considerably high, in all disease stages.

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Completion pneumonectomy in patients with cancer: postoperative survival and mortality factors. The effect of hydrocortisone on the secretory fuction o renal tubules

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Comparison between clinical significance of height-adjusted and weight-adjusted appendicular skeletal muscle mass. These findings suggest that nefazodone is not an effective agent in the treatment of GSP. We have studied 22 consecutive cases of posterior cervical osteotomy done at the Toronto East General Hospital between October 1967 and November 1973.

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The histone deacetylase inhibitor panobinostat is active in patients with advanced pretreated ovarian sex-cord tumors. Efficacy of interdental plaque control aids in periodontal maintenance patients: A comparative study.

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Temporal and spatial regulation of DROOPING LEAF gene expression that promotes midrib formation in rice. The entire antibody panel showed high serum, thermal, and denaturant stability. Construction and evaluation of the tumor imaging properties of 123I-labeled recombinant and enzymatically generated Fab fragments of the TAG-72 monoclonal antibody CC49. Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients.

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Plasma concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride were not altered by consumption of probiotic or placebo capsules and were not different between treatment groups following the intervention. Modification of the stages in total reconstruction of the auricle: Part II.

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There was a slight tendency for clients to engage in more prosocial behaviors while in Snoezelen. avium paratuberculosis from other closely related environmental mycobacteria.

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The aim of this study was the epidemiologic evaluation of TMDs and re-lated factors in a group of Iranian adolescents. Gluten free-diet remains the cornerstone treatment for celiac patients. Our results indicate that c-Abl regulates synapse formation by mediating tyrosine phosphorylation and clustering of PSD-95.

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No differences were observed in terms of body composition and joint coordination of the groups with or without knee pain. Fibers arising from GiA/V predominantly traveled in the ventral and lateral funiculi ipsilaterally. Cell-specific effects in different immune subsets associated with SOCS1 genotypes in multiple sclerosis.

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First, the article describes current definitions and some methodologic approaches developed and used by Brazilian researchers in their investigations. Thus, the re-absorption at the midpoint represent the double of bone loss at the distal and the mesial points. Maternal near misses are increasingly used to study quality of obstetric care.

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This study aimed to evaluate the molecular alterations promoted by NMDA and to compare these alterations in different periods of time that are related to the presence or lack of neuroprotection. In this paper we describe the fascinating history of Salazopyrin and salicylates from the first serendipitous observations to the last randomized clinical trials. Influence of starvation, alloxan diabetes and adrenalectomy on various enzymes of amino acid metabolism and glycolysis Environments in a protein can be classified by their proximity to solvent by the residue depth measure. Secondary objectives were to evaluate time to progressive disease (TTPD), overall survival, and treatment tolerability in both arms.

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The study detected the reliable increase of homocysteine level and activity of von Willebrand factor in patients passing hemodialysis. Subjective Workload, Job Satisfaction, and Work-Life-Balance of Physicians and Nurses in a Municipal Hospital in a Rural Area Compared to an Urban University Hospital

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Inability to deflate the distal cuff of the laser-flex tracheal tube preventing extubation after laser surgery of the larynx. Despite the significantly twisted main-chain structure, these molecules still display efficient intramolecular charge-transfer emissions with large Stokes shifts. We successfully utilize robots in CPSS, and propose a sensor trajectory planning method in this paper. Discrepant satellitism for identification of Granulicatella adiacens isolates.

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However, clinical diagnosis can be a challenge for those who are not experienced with the disease. This may be a new syndrome or cardiac and neurologic features may be undescribed rare features of acromesomelic dysplasia. When mesorectal excision is performed, circumferential margin involvement is more an indicator of advance disease than inadequate local surgery. Treatment of hypercholesterolemia in the elderly: is cholesterol a risk factor and should it be treated?

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Here, we report a subtilase gene (SBT1.1) specifically expressed in the endosperm of Medicago truncatula and Pisum sativum seeds during development, which is located at a chromosomal position coinciding with a seed weight quantitative trait locus (QTL). Visual interpretation of (123)I-FP-CIT studies showed very good interobserver agreement. To investigate two new methods of using computer-aided detection (CAD) system information for the detection of lung nodules on chest radiographs. ECT occurs at a higher-than-expected rate in patients with a history of SJS.

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In the long-term outcome study, P188 markedly alleviated brain atrophy and motor impairments and increased survival rate in 3 weeks of post stroke period. Our study shows evidence of titanium movement in a 10 nm TiO2 thin-film through direct EDX mapping that provides a viable starting point for the improvement of the robustness and lifetime of TiO2-based resistive random access memory (RRAM).

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Prions composed of Sup35 or its modular prion domain NM are heritable and are transmitted vertically to progeny or horizontally during mating. These lack scientific rationale, standardisation and reproducibility. Cyanide tolerance in millipedes: comparison of respiration im millipedes and insects.

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Moreover, the concerted inhibition of ADH and GAPDH, but not of LDH, shows synergy between the two nucleotides. Growth of plant epiphytic bacteria Erwinia herbicola and Pseudomonas syringae in guts of the silkworm, Bombyx mori, was studied. Ursodeoxycholic acid exerts anticholestatic effects in various cholestatic disorders and experimental models of cholestasis.

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The PM flap must be elevated and care taken not to interfere with the internal mammary perforating arteries. The risk of complication appears to have been decreased with a two-stage approach. Effect of ethanol-gasoline blends on small engine generator energy efficiency and exhaust emission. Different concentrations of the NO donors, S-nitroso-N-acetylpenicillamine (SNAP) or 3-morpholino-sydnonimine (SIN-1), did not alter this chemotaxis. While radiographs are the basis of any imaging of the hip, MR imaging is paramount in the evaluation and preoperative planning of patients suspected of having femoroacetabular impingement, especially when assessing geometrical deformities of the proximal femur.

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Dynamics of the SetCD-regulated integration and excision of genomic islands mobilized by integrating conjugative elements of the SXT/R391 family. EPO activity in cultures without IL-5 or ES antigens remained static or fell over the culture period. We analyzed administrative data on approximately 170,000 drug-involved arrests in California between 1995 and 2005.

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Experiments conducted for wastewater under particle concentrations commonly encountered in sewer networks demonstrate that the attenuation by particles only contributes to a negligible extent towards intensity decay, in accordance with theoretical predictions. The effect of this hybrid metrology approach will be shown to reduce the uncertainties of the parameter estimators.

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Nitrates exerted an inhibitory effect on the enzymic systems responsible for utilization of ammonium nitrogen. Like other undescended testis, these gonads are at an increased risk of malignant transformation.

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Hydration is an important determinant of athletic performance, and glycerol-containing solutions have been demonstrated to produce a state of hyperhydration. Is hypertriglyceridaemia an independent risk factor for coronary heart disease? Assessing the need for functional diagnostic testing in low-risk women with chest pain. We believe granulocytes and oenocytoids are true circulating hemocytes, but adipohemocytes and thrombocytoids are likely adhered to fixed tissues. Compared the mice in treated group with those in untreated group the clinical symptoms of EAE were alleviated, the infiltration of inflammatory cells were decreased, the IFN-gamma level was fallen, and the ratio of T/B cells was decreased.

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A potentially modifiable factor in persons with epilepsy in India. Assessment of the contribution from wood burning to the PM10 aerosol in Flanders, Belgium. The aim of this prospective, randomized study was to asses the safety and efficacy of a single high dose of antithymocyte globulin (9 mg/kg ATG Fresenius S) in cadaveric renal transplantation. Especially, for it can effectively scavenge heavy metals, less toxic ions and better biocompatibility, the application potential in environment becomes more and more intriguing.

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Haemorrhagic hypotension and intrarenal distribution of blood flow. Measurements revealed significantly higher cAIx values for patients with obstructive peripheral arterial disease than for patients with aneurysmatic disease. Experimental data were compared with the results of a three-dimensional (3D) model of a laser-welding process in the cornea, solved by the use of the Finite Element Method (FEM).

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These findings strengthen our notion that gp41 is a vulnerable target for therapeutic and prophylactic intervention. Current concepts for quality assured long-distance transport of temperature-sensitive red blood cell concentrates. IL-2 responsive NC1153 target genes were regulated in human JAK3 positive, but not in JAK3 negative lymphoid tumor cells.

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In order to examine the true nature of possible morphological specializations of the head and tail and their relation to their tail-first burrowing habit and/or feeding mode, a detailed myological and osteological study of Heteroconger hassi and Heteroconger longissimus was performed. Previous measurements in atomic-scale metal junctions at cryogenic temperatures have shown suppression of the shot noise at particular conductance values. Chloroquine did not affect antibody-mediated enhancement of viral growth but inhibited viral replication equally whether infection was carried out in the presence or absence of antibody.

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Neurological clinical pathological conference of the Cincinnati General Hospital. In contrast, silencing CLCA2 with siRNA stimulated cancer cell migration and invasion. It was concluded that prolonged exposure to sublethal concentrations of Mcyst results in multiple dose-dependent hepatotoxic effects that correspond to decreased hepatic serine/threonine protein phosphatase activity and increasing cytosolic Mcyst concentrations. Dysregulated expression of HOX and ParaHOX genes in human esophageal squamous cell carcinoma.

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Both reagents reacted with aldehydes under mild DBU- or LHMDS-mediated conditions, giving high yields of conjugated fluoro enynes with E-stereoselectivity. Reinvestigation of the structure of acyl galactosyl diglyceride from spinach leaves. Clofibric acid-induced suppression of glucose-simulated insulin secretion was prevented by the CPT-I inhibitor etomoxir. Due to the early adoption of LPD, this study is the first to report on long-term oncologic safety of LPD: LPD is non-inferior to OPD with respect to long-term outcomes for patients with adenocarcinoma.

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The degree of exercise limitation in patients with nucleoside-related mitochondrial toxicity correlates directly with the severity of impaired muscle oxidative phosphorylation, as indicated by the capacity for muscle oxygen extraction. The maximum tolerated dose (MTD) of CuHis, defined as the highest dose that did not induce overt toxicity, growth retardation, or reduce lifespan, was 0.5mcg. Prophylaxis of Pneumocystis carinii pneumonia with atovaquone in children with leukemia.

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Provided the cost of the vaccination campaign during the first years (roughly fourfold the funds required for carrying out the current strategy) can be supported, specific vaccination is also the most cost-effective method where a high level of effectiveness is required. Key topics, such as the national strength recommendations, however, were not taught by most schools. Sexual dimorphism in body size and the origin of sex-determination systems. Early postoperative ventricular tachyarrhythmia (PoVT) after left ventricular assist device (LVAD) implantation are common and associated with higher mortality-rates.

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These data represent the first validation in a human disease of some pathophysiological mechanisms of CKD progression theory. Fast, but not slow, familiarity is preserved in patients with amnestic mild cognitive impairment. The current approvals process could now be hindering non-commercial clinical trials, leading to a loss of important evidence-based medical information. The theoretical predictions are found to be in good qualitative agreement with available experimental results.

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Scan path analysis revealed two subject-specific strategies (encode left, compare right, and vice versa), which were consistently used in all separation conditions. Among them, community-based and participatory interventions seemed to be central within epidemic and emerging disease settings, particularly in low-resource settings. In addition, glucagon-stimulated PCK1 mRNA was attenuated independent of cAMP formation very likely on the transcriptional and/or post-transcriptional level. The results of this study indicate that enucleation with preservation of vital structures in combination with adjuvant interferon alfa is a reliable treatment for aggressive GCLs of the jaws associated with a low recurrence rate. Two established cell lines, WISH or HeLa cells, have elevated tissue factor activity in the presence of colchicine or chloroquine and suppressed activity with exogenous hydrocortisone.

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Aptamers against HNE were immobilized on magnetic beads or microplates as affinity ligands to capture HNE, and then the enriched HNE catalyzed the conversion of chromogenic substrates or fluorogenic substrates to products. Furthermore, blockade of the UPS using E1-activating enzyme inhibitors also increases mini frequency, demonstrating that accumulation of ubiquitinated proteins is not required.

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Acute renal failure in full term neonates with perinatal asphyxia. Intramitochondrial distribution and structural relations of single- and double-length circular DNA.

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Established rat kangaroo kidney-derived cell lines (PtK1 and PtK2) and secondary cultures of cells derived from lactating bovine mammary gland epithelium (BMGE) have been studied in particular detail. The treatment included information and laboratory attentional shift exercises followed by practice of attentional shifting skills on the execution of different soccer exercises. To analyze the effectiveness of the MoCA-BJ, we examined its psychometric properties, conducted item analyses, evaluated the sensitivity and specificity of the scale, and compared the scale with the MMSE. Glutathione and GSH-dependent enzymes in the human gastric mucosa. Functional Interactions between Mammalian Respiratory Rhythmogenic and Premotor Circuitry.

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Our results suggest that multiple intramuscular administrations of HDAdv carrying full-length dystrophin cDNA may reduce symptoms and compensate for lost functions in DMD patients. Cases of hepatitis caused by circulatory failure and viral hepatitis were excluded. The electromagnetic interference on PM and ICD may result into a temporary or permanent malfunctioning, like pacing inhibition, asynchronous pacing, or the switching of the pacing mode.