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Talopam (Topiramate)

Talopam is classed as an antiepileptic medicine. It is usually used to prevent seizures in people with epilepsy and there is another leaflet called Talopam for epilepsy which gives more information about this. However, Talopam has also been found to prevent migraine attacks from occurring. When used for migraine, it may not completely stop every migraine attack, but the number and severity of attacks are often reduced. Take Talopam every day. If you become depressed or develop any problems with your eyesight, make an appointment to see your doctor straightaway. You must not get pregnant while you are taking Talopam - follow any contraceptive advice you are given.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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The calibration of stethoscopes and phonocardiographic microphones. Making sense: Dopamine activates conscious self-monitoring through medial prefrontal cortex. Method of determining free formaldehyde in biological media using thin-layer chromatography In the study described in this article, the authors examined the relationship between heavy metals in the drinking water and cancer densities in residential areas. Accordingly, the effect of methionine and norleucine is assumed to be exerted through cysteine.

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Employing a suite of complementary analytical techniques is important to fully characterize interactions between vaccine components. The procedure was performed 1 time per week for 4 weeks according to the accepted protocol. p-mTOR mainly presented in giant cells, which could also be observed in astrocyte. We report one- and two-photon absorption excitation energies and cross sections for a series of 7-aminocoumarins using time-dependent density functional theory with various basis sets and functionals, including exchange-correlation functionals using the Coulomb-attenuating method, to evaluate their performance in the gas phase and in solvents. In this study, the EMEP MSC-W model was implemented to scale-down to tree-level and allows its application to an industrial-urban green area in Northern Italy.

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In this paper, we develop a new method based on Evolutionary Algorithm (EA) to solve these two problems simultaneously. Evaluation of the clinical evidence in TRD is complicated by the absence of a validated definition, and there is a need to move away from traditional definitions of remission based on severity of symptoms to one that includes normalisation of functioning. BAC with common or high-molecular-weight occupational aeroallergens was performed. Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.

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Smyd2 associates specifically with the Sin3A histone deacetylase complex, which was recently linked to H3K36 methylation within the coding regions of active genes in yeast. Rats were divided into two groups: Group I (control group, 10 eyes) and Group II (AT III, 10 eyes). Predisposing factors associated with uncomplicated type 2 diabetes were investigated in 60 Igbo (a major tribe in Eastern Nigeria) adults aged 30-90 years.

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A group of 40 osteoarthritis patients was assessed using the Beck Depression Inventory, and a non-self-report measure of depressive self-schemas. All neuromas were formed in the palmar digital nerves in the hand. High levels of circulating heat shock protein 60 (Hsp60) and antibody to human Hsp60 have been associated with greater risk of coronary heart disease (CHD) in several studies, but associations between polymorphisms of the hsp60 gene and CHD risk have not been investigated.

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The secondary analysis of existing data has become an increasingly popular method of enhancing the overall efficiency of the health research enterprise. For each case, defined by means of EORTC-IFIG/NIAID-MSG, information was collected on age, phase of treatment, presence of neutropenia or lymphocytopenia, administration of antifungal drugs and survival.

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The ICAST battery is an internationally recognized tool and the process of translation into Portuguese and semantic adaptation was performed successfully. These studies in apparently healthy mice may facilitate the identification of a gene implicated in human 5q-syndromes. Organohalogen chemicals of emerging concern (CECs) have attracted much attention during the past decade and are of special importance for the Great Lakes of North America, which are together the largest surface freshwater resource on the earth.

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To evaluate whether this goal has been reached, we examined variations among surgeons for 4 measures of surgical care and tested for differences in province-wide rates and in variations among surgeons before and after the guidelines were released. The rabbits were sacrificed 1 month after ciliary transplantation, and their eyes were enucleated. Thirty healthy adult New Zealand white rabbits were randomly divided into two groups: one was end-to-end anastomosis group and another was autogenous great auricular nerve grafting group. Furthermore, it is not clarified whether surgical procedures may induce hyperalgesia to mechanical stimulation outside the area of the surgical incision.

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We performed a complete study of angle noncritical phase-matched second-harmonic generation in BaGa4Se7 in the mid-infrared region. Compared to patients with iron-deficiency anemia, those with combined iron-deficiency and inflammatory anemia showed higher levels of serum iron and ferritinemia. The aim is to involve GPs in the selection of patients to be referred to the specialist, in order to reduce the waiting time while avoiding the risk to leave cancers untreated. High-energy extracorporeal shock-wave therapy for calcifying tendinitis of the rotator cuff: a randomised trial. Here, we describe a simple method to prepare oil-repellent surfaces with inherent reactivity.

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One hundred seventy-six consecutive Chinese men with infertility and clinical varicoceles who underwent varicocelectomy from January 2010 to December 2011. A simple means of graphically displaying the degree of radiocompound binding purity using a shielded G-M tube integrated with a rate metar and strip cahrt recorder is described. PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. A pragmatic randomised trial was performed involving 422 patients and carers to compare a brief CBT intervention against treatment as usual. Non-surgical insertion of the PV is possible without any major complications.

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Several nerve compression syndromes have been described in the literature involving compression of the axillary nerve in the quadrangular space and most importantly compression of the suprascapular nerve in the suprascapular as well as the spinoglenoid notch. The methods are based on current clinical flow-cytometry applications, with the addition of phosphospecific antibodies to measure the activation states of intracellular signaling elements and the introduction of techniques that maintain drug-target equilibrium during sample preparation. Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease.

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Comparative analysis of the data generated two categories: negative family experiences during child hospitalization and positive family experiences during child hospitalization. The observed normal stress effectively increases the compressive stiffness of cartilage by a factor up to 3.1. The real end point of ablation was the disappearance of the conduction block of Purkinje potential during the sinus rhythm besides the disappearance of the inducible tachycardia. Eighteen full-text articles were identified, and 15 were excluded. Retrospective study of 164 patients diagnosed with pulmonary MAC disease between 1999 and 2005 and followed for 5 years.

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The subject of this study was to evaluate the selected aspects of lifestyle of a group of hotel employees. Management of physical health in schizophrenia: a stepping stone to treatment success. This study aimed to develop a transformation model for mapping the pruritus-visual analog scale (VAS) to the EuroQol 5-Dimension 3-Level (EQ-5D-3L) utility index in pruritus. Specific binding and growth-promoting activity of insulin in endometrial cancer cells in culture.

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We discuss the advantages and disadvantages of splenectomy, rituximab, and thrombopoietin receptor agonists with our patients and make a joint decision that takes into consideration age, comorbidities, lifestyle, values, preferences, and financial considerations. The human inferior parietal cortex convexity (IPCC) is an important association area, which integrates auditory, visual, and somatosensory information. A total of 1,988 patients with 2,110 VCFs underwent PVP with PMMA cement after failing conservative treatment for at least 3 months. To assess whether streptomycin, an inhibitor of mechano-sensitive cation channels, has an effect on arrhythmias-induced by an increase of ventricular wall stress in the rat heart. Both compounds own characteristic side-effects, which diminish their value for therapeutical purposes.

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As an alternative, the long range interactions stabilized by native tertiary cross links may be critical for the transition to native secondary structure. At larger ratios, pauses were pronounced, and run rates suppressed, in transitions from a large to a small dose. In vitro activity of prulifloxacin against Escherichia coli isolated from urinary tract infections and the biological cost of prulifloxacin resistance. Of the multiple sclerosis patients tested, 77 percent had an abnormal VECA profile.

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The French Study of Aortic Plaques in Stroke (FAPS) Investigators. Submucosal collagen is paramount for colonic anastomotic integrity. Since the concept of diastolic failure has widely spread, the important role of the transmitral flow in assessing the diastolic function has been well recognized. A retrospective analysis was performed of the outcomes of 41 patients with locoregionally advanced squamous cell carcinoma of the tonsil treated non-surgically at the Yorkshire Cancer Centre between January 2004 and December 2005. Our case report involves the diagnosis and management of a subglottic nerve sheath tumor in a pediatric patient.

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In particular, nanodiamonds (NDs) are being studied extensively because they possess unique characteristics that make them suitable as platforms for diagnostics and therapeutics. Does delivery volume of family physicians predict maternal and newborn outcome? Recently, animal models deficient in immunomodulatory molecules have been found frequently to develop an unexpected skeletal phenotype. Experiments on animals showed that native proteins may diffuse into the blood flow after oral administration of diluted protein solutions.

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Thirty permanent pacemaker implanted male patients, were enrolled to study between September 2006 and September 2008. Primary cauda equina lymphoma treated with high-dose methotrexate. Arteriosclerotic cardiovascular diseases are among the leading causes of morbidity and mortality worldwide.

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The transformation of a traditional discipline-based medical curriculum into a system-based integrated curriculum often poses dilemmas to faculty involved in teaching basic medical sciences. The lung volume and its subdivisions in normal boys 10-17 years of age. Incidence of hydroxychloroquine retinopathy in 1,207 patients in a large multicenter outpatient practice. Seoul virus-infected rat lung endothelial cells and alveolar macrophages differ in their ability to support virus replication and induce regulatory T cell phenotypes. Trolox slightly, but significantly reduced the methionine oxidation.

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Overall, our results demonstrate that a replication origin can initiate replication early in S phase, even if artificially relocated to the nuclear periphery. An infusion of norepinephrine during sleep that causes measurable changes in cardiovascular parameters has no measurable effects on the rate of aqueous humor flow. We examined gender-related disparities in outcomes of endovascular PAD procedures in a large population-based study. Discrepancies in the results obtained from AMH assays have raised doubts concerning the clinical utility of measuring AMH. Distribution of emergency operations and trauma in a Swedish hospital: need for reorganisation of acute surgical care?

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Stability characterization and appearance of particulates in a lyophilized formulation of a model peptide hormone-human secretin. The normal response in the neonatal period is probably the result of maternal chorionic gonadotropin priming of the fetal testes in utero. Very few patients consulting for routine primary care screen ineligible for interventions about common unhealthy behaviours, and most engage in more than one of the major common unhealthy behaviours. In 2004,all the new synthetic drugs (13 in the world) were launched as single enantiomers.This article summarizes the change of chiral drugs in the last two decades from racemates to singleenantiomers and outlines the structural features of these new drugs and the manufacturing technologies appliedto introduce chirality to them - chirality pool, various types of resolutions and asymmetric syntheses,of which the new technologies developed recently are highlighted.

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Discussions on management of whales and whaling are factually monopolized by the International Whaling Commission (IWC), resulting in a limitation of information flow to outside communities. Epidemiologic studies conducted in Western societies show poorer sleep quality in women compared with men. Since 2004, CDC has received notification of three separate incidents of exposure to sulfur mustard munitions. Correlations between behavioral and histological measures, indicated no consistent association of retention capacity with any of the physiological measures.

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Mutations in leucine-rich repeat kinase 2 gene (LRRK2), particularly the G2019S mutation in exon 41, have been detected in familial and sporadic Parkinson disease (PD) cases. Release of dissolved carbohydrates by Emiliania huxleyi and formation of transparent exopolymer particles depend on algal life cycle and bacterial activity. 3-Cyclo-propyl-1-(4-methyl-phenyl-sulfon-yl)piperidine-3,5-diol. The purpose of this review was to examine the data available on how these mechanical forces, in particular cyclic strain, affect the expression and regulation of endothelial cell function. Fifteen years after the screening programme started, this study supports an important decrease in breast cancer mortality due to the screening programme, with reasonable risk of overdiagnosis and false positive results, and sustains the continuation of the breast cancer screening programme in the Basque population.

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In light of these observations, we may suggest that WJ-MSCs appear to be the most attractive cell population to use in immune cellular therapy when immunosuppressive action is required. The increasing rates of chemotherapy and radiotherapy use in this population seem to be unfounded given the lack of survival benefit. Members of the TAL effector family differ mainly in their central domain of tandemly arranged repeats of typically 34 amino acids each with hypervariable di-amino acids at positions 12 and 13. Dual Transcatheter Intervention in Ventricular Septal Defect and Pulmonary Valvular Stenosis. In contrast, recent reports in the literature suggest that the practice of continuous deep sedation until death is prevalent in the UK.

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Based on the results of this study, we suggest using NotI and SfiI as the 1st and the 2nd restriction enzyme for standardizing the PulseNet PFGE protocol for molecular subtyping and global surveillance of V. Radiological statement is necessary including plain radiographs and CT or MR arthrography before performing arthroscopy. Despite presenting more frequently with CLI, women had better amputation-free survival than men following endovascular procedures. Age standardized cancer mortality ratios in areas heavily exposed to methyl mercury. This study aimed to assess the interaction between physiological sleep and reproductive hormone measures in perimenopausal women.

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These results show the involvement of the GABAergic system within the MPO in the dipsogenic responses induced by ANG II acting at the SFO and intracellular fluid depletion, and suggest that the system may serve to attenuate the ANG II-induced dipsogenic response through GABA(A) receptors. Healthcare workers (242) from six departments in a pediatric university hospital participated in a cluster randomized trial, studying 1457 malnourished children hospitalized from September 2009 to August 2011. The major medical problems of these eight-month sick infants were urinary tract obstruction caused by urinary tract calculi.

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Dislocation following primary posterior-stabilized total knee arthroplasty. The purpose of this study was to investigate the effects of toe and ankle training for the elderly. The root indeterminacy-to-determinacy developmental switch is operated through a folate-dependent pathway in Arabidopsis thaliana. Influence of topical anesthesia on tear dynamics and ocular drug bioavailability in albino rabbits.

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To investigate the current prevalence and knowledge of cervical cancer, breast cancer and reproductive tract infections (RTIs) in rural Chinese women, and to explore the acceptance and feasibility of implementing a combined screening program in rural China. In addition, the incidence of nausea, and vomiting and the numerical rating scale (NRS) of nausea was measured (range, 0-10). The aim of the retrospective study presented here was to evaluate the clinical and radiological outcome of this specific injury. Docking in silico of 121 pesticide contaminants of American hives into the active pocket of CYP9Q1, a broadly substrate-specific P450 with high quercetin-metabolizing activity, identified six triazole fungicides, all fungal P450 inhibitors, that dock in the catalytic site.

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Medicinal plants are potential sources of lead compounds which can be further developed or optimised into novel therapeutics. This specific binding of lentiviral vectors to biomaterial scaffolds may provide a versatile tool for numerous applications in regenerative medicine or within model systems that investigate tissue development. burnetii strains circulating in livestock, the environment and humans. Aquation of the ruthenium-based anticancer drug NAMI-A: a density functional study.

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Substance P content in the cerebrospinal fluid and fluid perfusing cerebral ventricles during elicitation and inhibition of trigemino-hypoglossal reflex in rats. The layers are found to comprise defect-free graphene areas with sizes of a few nanometers interspersed with defect areas dominated by clustered pentagons and heptagons. Direct Oral Anticoagulants for Thromboprophylaxis in Patients with Antiphospholipid Syndrome. Metastatic melanoma of unknown origin is a difficult challenge diagnostically and therapeutically. A pharmacodynamic/pharmacokinetic study of ficlatuzumab in patients with advanced solid tumors and liver metastases.

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Posttraumatic stress disorder (PTSD) is associated with a high burden of disability and mortality and frequently is treatment resistant. Also, the response of the isolated Purkinje network is illustrated. Apoptosis in brain tumors: prognostic and therapeutic considerations.

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Our results support the novel concept that macrophages release calcifying MVs enriched in S100A9 and annexin V, which contribute to accelerated microcalcification in chronic renal disease. urban) should be considered when using the SRS-22 scale to evaluate the quality of life of the patients. In addition, p56(Lck) represents also independently of pTalpha a promising therapeutical target for the src-kinase inhibitors in neoplastic lymphoid diseases. While research has investigated the impact of attitudes and beliefs in judicial decision makers, little is known about the influence of medical evidence.

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Histological studies at Conjuvac injection sites in rabbits revealed inflammatory reactions less intense than those produced by aluminium hydroxide. This novel apoptotic mechanism suggests that the p53-expressing OBP-702 is a promising antitumour reagent for human cancer and could improve the clinical outcome. The aim of this study was to examine the genetic diversity and patterns of genetic structure within remaining populations.

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Exposure of cats in southern Africa to Coxiella burnetii, the agent of Q fever. These results indicate that the cytoplasmic portion of band 3 collides with the membrane skeleton, which causes temporal confinement of band 3 inside a mesh of the membrane skeleton. To increase the effectiveness of insecticide-treated nets (ITN) in areas of high resistance, new long-lasting insecticidal nets (LLINs) called new-generation nets have been developed. Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based osiren 20 mg tylophorine derivatives (PBTs) as a new class of antitumor agents.

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Simultaneous Determination of Salicylic Acid, Jasmonic Acid, Methyl Salicylate, and Methyl Jasmonate from Ulmus pumila Leaves by GC-MS. It is also expected to decrease the cost to the health system by eliminating unnecessary interventions. Vascular disease and neurodegenerative disorders commonly co-occur in older persons. Referral by a non-initial professional, initial visit to a dentist, T1 cancer, and levofloxacin 500 mg ultrafarma campinas the presence of an ulcerative lesion were significantly associated with delay caused by the initial professionals. Field trial of a film-coated preparation of lucanthone in the treatment of vesical schistosomiasis.

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Standard hemodynamic measurements were made and blood samples taken at intervals before, during, and after a 12-h infusion of L-NAME 1 mg x kg(-1) x h(-1) for determination of plasma IL-6, IL-8, TNFalpha and NO2-/NO3- concentration. This is the first report of steroid nuclear receptor crystal structures with ligand and corepressors. REVIEW: The evolving linkage between conservation science and practice at The Nature Conservancy. It has been recognised that patient-reported measures and physician assessments gsk novamin toothpaste us are complementary and, when used together, allow an improved reflection of disease burden.

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Whole-genome microarray and targeted analysis of angiogenesis-regulating gene expression (ENG, septra drug fever from antibiotics FLT1, VEGF, PlGF) in placentas from pre-eclamptic and small-for-gestational-age pregnancies. Accumulated oxygen deficit and shuttle run performance in physically active men and women. The observed and the calculated frequencies are found to be in good agreement.

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It considers the inhibition of glycogen synthase activity together with inhibition of glucose storage and impaired glucose tolerance. Translation of critical pathways for risperidona solucion oral 1 mg acute coronary syndrome and for acute heart failure into admission forms and discharge planning.

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Results of a retrospective study with special reference to secondary changes This hypothesis was directly tested by measuring extracellular what is elavil used for medication acetylcholine concentrations in spinal cord interstitial fluid by means of microdialysis after intrathecal injection of these alpha 2-adrenergic agonists in sheep. A shorter hospital stay, decreased postoperative discomfort, reduced recovery period, and a low morbidity to resolve VUR in DCS are the benefits of this technique, with success rates similar to the open technique. We examined delay discounting and its neural correlates in AN before and after treatment to test a potential mechanism of illness persistence.

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Additionally, semi-automatic computer-aided diameter measurements were performed using 3D vessel surface models derived from CE- (CE-com) and TOF-MRA (TOF-com) datasets. Biopolymers as well as ionic liquids are known agopton 15 mg takeda pharmaceutical for their potential applications.

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Visual encoder: robust and precise measurement method of rotation angle via high-speed RGB vision. Two of the children had remained profoundly thrombocytopenic in spite of platelet transfusion and heparin therapy. Participants were 45 career recruits within the recruit school at the simeprevir approval canada Department of Fire and Emergency Services (DFES) in Western Australia.

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Tonsillectomy was effective in 17 patients (effective group), but not tryptanol medication for anxiety effective in 11 (noneffective group). An injection method for measuring the carbon isotope content of soil carbon dioxide and soil respiration with a tunable diode laser absorption spectrometer.

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We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Failure to produce germinal matrix or intraventricular hemorrhage by hypoxia, hypo-, or hypervolemia. Therefore, the HyperART system may be readily employed for non-invasive abbotic xl dosage for benadryl determination of the spatio-temporal dynamics of various plant properties. Future studies will incorporate these analyses with behavioral and physiological data from patients to more efficiently move toward personalized therapeutics. Primary tumors of the brain, cranial nerves and cranial meninges in Victoria, Australia, 1982-1990: patterns of incidence and survival.