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Sanamidol (Omeprazole)

Sanamidol is a benzimidazole with selective and irreversible proton pump inhibition activity. Sanamidol forms a stable disulfide bond with the sulfhydryl group of the hydrogen-potassium (H+ - K+) ATPase found on the secretory surface of parietal cells, thereby inhibiting the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen and suppressing gastric acid secretion. This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors. Check for active clinical trials using this agent.

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This method is safe and effective and can provide information which is useful in the management of certain critically ill patients. We demonstrate that beta-carotene provides protection against singlet oxygen-mediated lipid peroxidation, but does not slow free radical-mediated lipid peroxidation. Outcomes include fewer codes indicating violent situations, a reduction in physical restraint and sitter use, and fewer reports of safety incidents involving agitated patients. For the intervention group, the informed consent process was designed with further revisions based on REA findings.

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Health-Related Quality of Life of Young Adult Survivors of Childhood Cancer: A Review of Qualitative Studies. Currently, there are limited data to support the efficacy of CPAP for arrhythmia prevention or treatment.

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maimaiga DNA showed that soil background DNA and remaining co-extracted contaminants are critical factors determining detection sensitivity. Changes in our microbiota can modify obesity and the immune underpinnings of metabolic diseases such as Type 2 diabetes. Corneal astigmatism in the patients undergoing MSICS was stable at 1.5 months after the surgery. Against a backdrop of rising healthcare costs, variability in care provision and an increased emphasis on patient satisfaction, the need for effective interventions to improve quality of care has come to the fore.

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A model is presented that quantitatively predicts both the spectral phase and the spectral interference measured in the sidebands. Closed continuous irrigation as a treatment for infection in the hand. Data on the time from referral to surgery, postoperative complications, and revision surgery are also reported. These results demonstrate that SMN levels are dependent on synaptic activity, implying that SMN may have important neuron-specific functions downstream of synaptic activation. On the association between perinodal astrocytic processes and the node of Ranvier in the C.N.S.

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This study evaluated the methylation profile and the tumor-suppressive function of the small heterodimer partner (SHP, NR0B2) in the development of human hepatocellular carcinoma (HCC). Experiments were carried out on 30 rabbits with adrenalin glaucoma. Based on a literature review and personal experience in liver transplantation for CD, we show the status quo of indication, allocation, and outcome as well as potential strategies to overcome long waiting times and organ shortage. This Dutch epidemiological study used primary care-based data to examine changes in the incidence of eating disorders in the 1990s compared to the 1980s.

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Intraabdominal pressure never exceeded 6-8 mmHg during the intervention. Griffith theorized mechanisms by which a pathogenic protein could encipher its own replication blueprint without a genetic code. Only two-thirds of the sample had at least one full remission by 4 years, and almost half of them subsequently relapsed. To investigate the effects of exercise and/or tea catechin supplementation on muscle mass, strength and walking ability in elderly Japanese women with sarcopenia. This novel technique required the multidisciplinary expertise of anesthesiologists, radiation therapists, medical dosimetrists, medical physicists, and radiation oncologists to ensure a safe and reproducible treatment course.

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A velocity reference model, representing the desired closed-loop vehicle dynamics, is integrated with an IBVS kinematic model to predict the future trajectories. This study aimed to identify whether preoperative imaging and/or biopsy provide diagnostic accuracy. This survey was conducted from June 2014 through July 2015 with the main goal of investigating the prevalence and associated risk factors of coccidiosis among village and exotic breeds of chickens in Maiduguri, Northeastern Nigeria. Association of maternal obesity before conception with poor lactation performance. Expression of CD39 mRNA is altered in the peripheral blood of patients with allergic asthma.

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From 1980 to 1994, 76 evaluable patients underwent surveillance at the Tom Baker Cancer Centre. Basic and theoretical study on esophagocardioplasty with a pedicle gastric flap In this study, we investigated the regulation of PEDF in type 2 diabetes in relation to fat mass and insulin resistance before and after the use of metformin for treatment.

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A comparative study of keratin expression between conventional and clear cell syringoma showed that there was no difference in the immunoreactivities. Direct Access to Multifunctionalized Norcamphor Scaffolds by Asymmetric Organocatalytic Diels-Alder Reactions. Splenic artery ligation significantly reduced the portal pressure and also decreased the fatality in excessively hepatectomized rats. The homology of this chromosome 21 duplicated region with the pericentromeric regions of chromosomes 13, 2, and 18 suggests that the mechanism involved is probably similar to pericentromeric-directed mechanisms described in interchromosomal duplications.

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The state estimates are predicted according to the continuous-time state equation between observation time points, and then updated with the new measurements obtained at discrete time instants, yielding physically more meaningful and more accurate estimation results. Renal cell cancer correlated with occupational exposure to trichloroethene.

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Complementary surface analysis techniques, such as atomic force microscopy (AFM), ellipsometry, and fluorescence, provided the univocal characterization of the realized structures in the solid state. In addition, the inhibited SREBP-1c- mediated lipogenesis caused by SSC may also contribute to alleviating fatty liver. Primary cultures of rat Sertoli cells were prepared from 10-d-old rats. For continuous risk factors, investigators selectively present contrasts between more extreme groups, when relative risks are inherently lower.

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We analysed the misdiagnoses in C-choline PET imaging in brain tumours with the aim of improving the accuracy of diagnosis with C-choline PET imaging. Influence of Verapamil and Cyclosporin A on bile acid metabolism and transport in rat liver slices. Pregnancy, posture, cold, circadian rhythm, and skin conditions increased spasticity and were measured using objective clinical tests. To assess the value of transvaginal sonography (TVS) in the diagnosis of heterotopic pregnancy (HP) in the first trimester after in-vitro fertilization with embryo transfer (IVF-ET).

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Pulmonary findings in patients who died of ARF presented four histopathological patterns: DAD, pulmonary edema, LIP and alveolar hemorrhage. Hemodynamic consequences of the combination of isoflurane anesthesia (1 MAC) and beta-adrenergic blockade in the dog.

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In addition, the present results supported the former speculation, i.e., covellite might be converted from chalcocite during the leaching experiments, and the elemental sulfur may partially be the derivation of covellite and chalcocite. Pip amplifies plant defence responses and acts as a critical regulator of plant systemic acquired resistance, defence priming and local resistance to bacterial pathogens. As cognitive dysfunction is a common marker of neuropsychiatric disorders, MEG is emerging as an important investigatory tool in neuropsychiatry. High-dose levofloxacin (L) (1,000 mg) was as active as moxifloxacin (M) (400 mg) in an early bactericidal activity trial, suggesting these fluoroquinolones could be used interchangeably. The purpose of our study was to identify the proteins and investigate the differences, if any, between protein components of the matrices of calcium oxalate (CaOx) and calcium phosphate (CaP) crystals induced in vitro in whole human urine of healthy individuals and kidney stone patients.

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The outcome has been favorable, but long-term follow-up is necessary for full assessment of those patients. Explanatory Item Response Models: A Generalized Linear and Nonlinear Approach by P. Our results support the contention that screen-based simulators are good devices to acquire technical skills of crisis management.

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Significant changes in the levels of copper, iron, Hb, epinephrine, norepinephrine, and serotonin were observed. A reduction of morgue activity suppressed grim-reaper-induced cell death in Drosophila.

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To date, no protein domain has been identified that binds specifically to Ptdlns(3)P and thereby recruits/activates downstream effectors of Ptdlns(3)P signaling. In fact, the tapping task is associated with significantly shorter behavioral and polysomnographic sleep onset latencies and with a greater proportion of slow-wave sleep (SWS) during the transition from wakefulness to sleep compared with the RTT. All 3 drugs induced a similar rise in the content of the dopamine metabolite homovanillic acid (HVA) in the nucleus accumbens, whilst the changes in HVA observed in the neostriatum were in the rank order in which these drugs produce extrapyramidal side effects. Unfortunately, these guidelines provide inadequate warning to asymptomatic individuals with subclinical atherosclerosis who are unaware of their high-risk status and are not aggressively treated by their physicians who follow the existing recommendations. Semantic descriptor ranking: a quantitative method for evaluating qualitative verbal reports of visual cognition in the laboratory or the clinic.

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Fine mapping, haplotype construction, and resequencing will provide a unique opportunity to study the pathogenesis of septal defects and shed light on molecular mechanisms of septal development. Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: in vivo assessment by intravascular ultrasound and magnetic resonance imaging. To expand this information, we performed a case-control study genotyping 130 single nucleotide polymorphisms (SNPs) in 82 biopsy-proven GCA patients and 166 healthy controls from the Spanish population. Distinguishing disordered regions from ordered regions in protein sequences facilitates the exploration of protein structures and functions. Bacteriologic cure was attained in all but one instance, and effective serum, bile, and pleural fluid drug levels were demonstrated.

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A hyperpolarization similar to that recorded in the cell body also occurred in the neuronal processes within the neuropile, where synaptic contacts are made. The patient data were accessed for age at surgery, International Prostate Symptom Score, prostate volume, preoperative serum prostate-specific antigen level, history of acute urinary retention, and surgical approach (open vs transurethral resection of prostate).

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Noise phobia, cognitive dysfunction, separation anxiety, attention-seeking behavior, and medical causes. SAMe appears to be as effective as NSAIDs in reducing pain and improving functional limitation in patients with OA without the adverse effects often associated with NSAID therapies. Hepatic abscesses have been reported as a rare complication of diverticulitis of the bowel. Good agreement between experimental and calculated spectra makes it possible to clearly distinguish between nonrelativistic and relativistic mechanisms of harmonic generation.

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Electronic databases were searched systematically for studies examining policy making in public health nutrition in high-income, democratic countries. In this work, the antihyperglycemic and antihyperlipidemic effects of CQA-rich Pandanus tectorius fruit extract (PTF) was investigated in diabetic db/db mice.

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Our findings suggest a possible cooperation of growth factors, cell cycle proteins, and transcription factors during the development of H. Catechol-induced inactivation of SODs was correlated with the auto-oxidation of the catechol compounds to their corresponding ortho-quinone derivatives, which was found to be non-dependent on the presence of enzymes. Electromyographic abnormalities included fibrillation potentials.

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Clinicopathological features of esophageal cancer simultaneously associated with gastric cancer. Effects of treatment programs on the acquisition of basic skills. Mpg), an enzyme that initiates BER, mediates alkylation-induced whole-animal lethality and cytotoxicity in the pancreas, spleen, retina, and cerebellum, but not in the kidney. Future research requires more robust study designs incorporating objective outcome measures. We compared recurrence of pain and pancreatic function between groups for over 3 years of follow-up.

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An anonymous questionnaire made up of 43 items was drafted and delivered to a sample of 123 nurses at 2 university hospitals in Rome. Clinical implications and directions for future research are discussed. By measuring the time constant for the polarization buildup and enhancement as a function of the microwave field strength, we are able to compare models of polarization transfer, and show that the major contribution to the bulk polarization arises via direct transfer from electrons, rather than transferring first to nearby nuclei and then transferring to bulk nuclei in a slow diffusion step. We implanted depth electrodes in 11 patients for surgical evaluation of intractable epilepsy. The role of lymphadenectomy in the management of endometrial carcinoma remains controversial in gynecologic oncology.

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The arm was extricated without sacrificing additional forearm stump length by reversing the worm mechanism of the meat grinder. Somatosensory evoked potentials elicited by stimulating two fingers from one hand--usable for BCI? In this report, we describe an unusual patient who, 31 years after experiencing an atypical preeclampsia-eclampsia presentation known today as the HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), developed CAPS, which seemed to complicate a diagnosis of primary antiphospholipid syndrome. To critically review published literature for treatment-related outcomes for bilateral inferior turbinate reduction (IFTR) via either microdebrider-assisted turbinoplasty (MAT) or radiofrequency turbinoplasty. Correction: texting teens in transition: the use of text messages in clinical intervention research.

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Initiation of an emergency department pharmacy program during economically challenging times. Changes in cell-to-cell contact and distribution of cytoskeletal components were investigated during in vitro culture of cattle oocyte cumulus complexes (OCC). Four phages were extracted from Lake Michigan on the same bacterial host, exhibiting similar morphological characteristics as shown under transmission electron microscopy. In a nationwide cohort study, the incidence of CC and LC continued to increase from 2002 to 2011.

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Selected human leukocyte antigen class II polymorphisms and risk of adult glioma. All patients on long term tamoxifen should be annually screened for endometrial pathology. The effects of serum from dermatitis herpetiformis cases on the spreading property of hvaluronidase. Ease of use, convenience, confidence in dosing accuracy, and improved quality of life are just a few of their advantages. Radiostereophotogrammetric analysis was used to measure rotations and translations between the prosthesis and bone.

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However, the scope and usability of the majority of current integration tools fail to deal with the fast growing and highly dynamic nature of biomedical data. Several toxicity profiles were observed depending upon the chemical structure of the compound in question. Initially lipase from various microbial sources and immobilization support composition was screened to obtain a robust biocatalyst. Self-monitoring as a mediator of weight loss in the SMART randomized clinical trial.

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We applied these methods to human leukemia cells growing in culture and each method resulted in excellent yields of RNA (typically 23 micrograms/million K562 cells, 13 micrograms/million HL-60 cells) over a wide range of cell concentrations (1 x 10(5) - 3 x 10(7)/ml) and of good to excellent quality as judged by agarose electrophoresis and UV absorbance data (OD260/280 1.90-2.05). These proposed criteria may change as the DSM-V process progresses. While acting as a ureteral splint and safety valve ureterostomy, it offers access for antegrade radiologic and manometric studies and may be used in conjunction with indwelling splints.

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Human cathepsin L along with cathepsin S, K, and V are collectively known as cathepsin L-like proteases due to their high homology. These tissues provide microenviroments for de novo HSC formation, as well as HSC maturation and expansion. Glutathione (GSH) is present in all mammalian tissues as the most abundant non-protein thiol that defends against oxidative stress. These data potentially suggest a lack of epistatic interaction between GRIA2 and GRIA4 variants, regarding clinical outcomes in patients with MDD. Predictors of freedom from disease activity in natalizumab treated-patients with multiple sclerosis.

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Au nanorings (NRIs), which have the localized surface plasmon resonance (LSPR) wavelength around 1058 nm, either with or without linked antibodies, are applied to SAS oral cancer cells for cell inactivation through the LSPR-induced photothermal effect when they are illuminated by a laser of 1065 nm in wavelength. Wide local excision is commonly possible in most of the cases for therapy.

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Acute Antipsychotic Treatment of Children and Adolescents With Schizophrenia-Spectrum Disorders: A Systematic Review and Network Meta-Analysis. Findings from this study increased both the number of host species and known geographical ranges of both parasites and suggest potential vectors for these two trypanosomes associated with bats in rural areas of southern Ecuador. We explored racial/ethnic disparities in reports of smoking cessation advice among smokers who had visited a physician in the previous year. Pulmonary rehabilitation in patients with neuromuscular disease. Engineering microorganisms for production of isoprenoids is relatively easy, sustainable, and cost effective in comparison to chemical synthesis or extraction from natural producers.

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Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication. Primary bone marrow lymphoma: an uncommon extranodal presentation of aggressive non-hodgkin lymphomas.

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Overexpression of MLP in C2C12 myoblasts enhances skeletal myogenesis, whereas inhibition of MLP activity blocks terminal differentiation. Although studies in vitro and in experimental animals suggest that hyperinsulinemia may accelerate atherosclerosis, these data are not substantiated in patients with type II diabetes. Laparoscopic surgery would be useful for examination and a minimally invasive approach to tumors of the small intestine, especially on cases with the possibility of multiple tumors.

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Successful resuscitation with thrombolysis of a presumed fulminant pulmonary embolism during cardiac arrest. Neurophysiological analysis of the cauda equina in POEMS syndrome. Structure-activity relationship study of the cell-penetrating peptide pVEC. Restricting ourselves to 3D objects formed from two-dimensional (2D) cross-sectional adjacent slices (i.e., long bones), we present a method of contextual classification and results concerning the ulnar bone. Sleep problems are a common complaint in the majority of people suffering from depression.

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Here, we perform a systematic analysis of all let-7 miRNAs and find that a single let-7 family member, human let-7a-3 (and its murine ortholog let-7c-2), escapes LIN28-mediated regulation. The HGMF has great potential for reducing the labor required in quantitative microbiology, since it allows, with one filter, enumeration of microorganisms over a very large concentration range and therefore reduces the need to make dilutions.

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We experimentally implement label-free phase microscopy using wide-field digital interferometry (WFDI) techniques to retrieve quantitative volumetric data of articular chondrocyte dynamics. In order to ascertain the relationship between the hematopoietic-supporting activity of PA6 cells and their expression, we cultured a number of these cells for over 45 weeks and investigated the level at which they expressed several cell surface markers and membrane-bound growth factors.

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These results demonstrate that oligomer formation by a mutant htt fragment is strongly polyQ length-dependent in vitro and in vivo, consistent with a causative role for these structures, or subsets of these structures, in HD pathogenesis. It outlines the physiological changes that occur in the GI tract as a result of ageing, and discusses common GI disorders in older people. Allogeneic hematopoietic cell transplantation versus drugs in myelofibrosis: the risk-benefit balancing act. This chapter demonstrates the technique of terminal restriction fragment length polymorphism (T-RFLP), a fingerprinting technique which combines both detection and identification in a single method, with the added benefit of inbuilt controls which removes the risk of false negative results and in addition highlights potential false positive results.

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These cysts were detected by ultrasound during a febrile illness. Regeneration of transected ventral roots submitted to monomolecular filter tubulation (millipore). Objective To assess the skills of healthcare professionals in recognising pale stools. Psychosocial interventions to support women to stop smoking in pregnancy can increase the proportion of women who stop smoking in late pregnancy and the proportion of infants born low birthweight.

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Comparison of the effects of ventral medullary lesions on systemic and microinjection morphine analgesia. Kangaroos and wallabies have specialised limbs indikasi obat omeprazole 20mg capsule that allow for their hopping mode of locomotion. We then evaluated differences in interictal EEG activity between patients with and without these psychiatric comorbidities.

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Attention is drawn to the complication of degenerative osteoarthritis that is associated with posterior glenoid osteotomy. acyclovir ointment 5% dosage calculations The interventions presented could be used to improve journal clubs at other institutions. Anecdotal cases of partial or complete responses have been reported after ipilimumab therapy for stage IV melanoma with brain metastasis treated earlier by surgery or radiosurgery. To construct the RNAi eukaryotic vector of inhibitory member of the prohibitin (PHB-1) gene and observe the interfering effect in HEK293 cell line after the vector transfection. Noninvasive detection of coronary vasospastic angina using a double-acquisition coronary CT angiography protocol in the presence and absence of an intravenous nitrate: a pilot study.

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Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies. A reduction in myocardial contractility induced by lucen 40 mg somministrazione di the administration of volatile anesthetic agents was detected by Ees and PRSF, but not by FAC, Vcfc, or dP/dtmax x EDA(-1).

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Synthesis, characterization, DFT and biological studies of isatinpicolinohydrazone and bristamox suspension its Zn(II), Cd(II) and Hg(II) complexes. Aging, aortic arch calcification, and multiple brain infarcts are associated with aortogenic brain embolism. Dynamic planar solid phase microextraction-ion mobility spectrometry for rapid field air sampling and analysis of illicit drugs and explosives. Levels of fumonisin B1 in corn naturally contaminated with aflatoxins. We also provide operating characteristics to demonstrate how the MRQCS responds to increases in systematic and/or random error.

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Association between skin and joint involvement in patients with psoriatic arthritis treated with adalimumab: analysis of data from a German non-interventional irbesartan 150 mg obat apazol study. Aiming at the derivation of a generalized procedure for the straightforward preparation of particles fluorescing in the visible and near-infrared (NIR) spectral region, different swelling procedures for the loading of the hydrophobic polarity-probe Nile Red into nano- and micrometer sized polystyrene particles were studied and compared with respect to the optical properties of the resulting particles. Coding of FM sweep trains and twitter calls in area CM of marmoset auditory cortex. The objective of the present study was to explore the moderating effects of sleep disturbance, fatigue and vitality on self-reported oral-health status and oral-health related behaviours.

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