Letonal is a potassium-sparing diuretic that removes excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease. It also can be used in combination with other drugs to treat diuretic-induced low potassium (hypokalemia) and high blood pressure. Letonal also is used to counteract the effects of excessive adrenal aldosterone production (hyperaldosteronism) that can occur from a tumor in the adrenal gland or enlarged adrenal glands (hyperplasia of the adrenal glands). Letonal and its active metabolites are specific pharmacologic antagonists of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Letonal causes increased amounts of sodium and water to be excreted, while potassium is retained. Letonal acts both as a diuretic and as an antihypertensive drug by this mechanism. It may be given alone or with other diuretic agents that act more proximally in the renal tubule.
Other names for this medication:
Spironolactone,
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Aldazida,
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Aldozone,
Alexan,
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Expal,
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Lanx,
Letonal,
Osiren,
Osyrol,
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Spiron,
Spirono,
Spironolacton,
Spironolactona,
Spironolakton,
Spironolattone,
Spirotone,
Verospiron,
Xenalon,
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Infants at risk for development of brain white matter lesions can be identified by the concentrations osyrol generika medpadala of interleukin-6 and interleukin-1beta in amniotic fluid. Pharmacotherapy for post-traumatic stress disorder: systematic review and meta-analysis.
Use of Ayurvedic diagnostic criteria in Ayurvedic clinical trials: a literature review focused on research methods. Twelve female patients with bilateral HV and 12 healthy female controls walked while three-dimensional kinematic and kinetic data were measured. dose of clindamycin in malaria parasite Finally, we discuss the potential of miRNAs as a disease marker and a novel therapeutic target in MS. Next, we present a few applications of protein-containing GUVs to study domain assembly and protein partitioning into raft-like domains.