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Subcutaneous (s.c.), intraperitoneal (i.p.) or oral (p.o.) administration of the venom caused an antinociceptive effect in mice as measured by the acetic acid-induced writhing method and the hot plate test. We present the crystal structure of the tandem SH2 domain of Syk complexed with a dually phosphorylated ITAM peptide.

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A total of 738 cases with DSM-IV schizophrenia (all participants in the CATIE study) and 733 group-matched controls were genotyped for 492,900 single-nucleotide polymorphisms (SNPs) using the Affymetrix 500K two-chip genotyping platform plus a custom 164K fill-in chip. Different amounts of liquid were added into the premixed acid phosphate and oxide powders in order to study the effect of liquid-to-solid ratios on the properties of magnesium phosphate chemically bonded ceramics.

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