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Cycloxan (Cyclophosphamide)

Cycloxan is a cancer (chemotherapy) medication used to treat several types of cancer. Cycloxan is also used to treat certain cases of nephrotic syndrome (kidney disease) in children. In treatment of cancer, the initial course of Cycloxan is usually of 40 to 50 mg/kg given intravenously (IV) in divided doses over a period of 2 to 5 days. Other intravenous regimens include 10 to 15 mg/kg given every 7 to 10 days or 3 to 5 mg/kg twice weekly. Oral Cycloxan dosing is usually in the range of 1 to 5 mg/kg/day for both initial and maintenance dosing.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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There was an association between greater NPS at the first time point, and persistent use of these drugs, but changes in NPS between time points, did not explain such use. Nanomolar concentrations of OTA led to activation of caspase 3 with subsequent chromatin condensation and DNA ladder formation, both characteristic for cells undergoing apoptosis. Effects of inter-electrode spacing on complex fractionated atrial electrograms and dominant frequency detection. Effect of aldosterone and of plasma extracts on a rat heart-lung preparation.

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Home and everyday life hygiene is a key part of the public health strategy to reduce infectious disease, but an effective code of practice is required. This study compared the clinical outcomes of patients undergoing conventional and on-pump beating-heart coronary artery bypass grafting and evaluated the efficacy of an on-pump beating-heart technique for the surgical treatment of these critically ill patients. Due to lack of evidence of efficacy and safety, health care personnel should not advice pregnant women to use echinacea or elderberry against upper respiratory tract infection.

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Endoscopic finding revealed a huge ulcerative lesion that infiltrated from the antrum to the mid-body. Measuring quality of life in patients with coronary heart disease. These damage-related stimuli induce the secretion of molecular agents collectively termed danger-associated molecular patterns (DAMPs). On the adenosine deaminase of rabbit reticulocytes and erythrocytes Subjective distress is a common unmet need in psychosis, and can be treated.

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The Continuous Performance Test (CPT) is a valuable tool for assessing behavior in attention-deficit/hyperactivity disorder (ADHD). Interviews were transcribed and analysed both thematically and as narratives. Initially, we characterized cell-type-specific expression of GFP or RFP in cultured cell lines.

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The associated factors were estimated and compared by traditional and multilevel logistic regression analysis. A strategy for sequencing based on rolling-circle amplification on a microarray. To investigate the prognostic significance of pathologic response (PR) after transarterial chemoembolization (TACE) in cirrhotic patients resected or transplanted for hepatocellular carcinoma (HCC), and to identify predictors of complete pathologic response (CPR).

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Effects of transfected pIRES-p21(waf1)-p27(kip1) gene on the duplication of centrosomes and the proliferation of breast cancer cell line MCF-7 Radiation dose of patients undergoing transcatheter aortic valve implantation: a comparison between Edwards SAPIEN XT and Medtronic CoreValve aortic valve prostheses.

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The current study sheds light on the practical applicability of electronic nose for the effective industrial odor and gaseous emissions measurement. Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives. The aim of this study was to compare the availability of suitable vein, maturation rates, patency and complication rates of autogeneous elbow fistulas in diabetics and non-diabetics at a single centre where an autogeneous vein only policy is employed. Highly pathogenic avian influenza A(H5N1) has been causing unprecedented global outbreaks since 2003 and many human cases with a high case fatality rate have also been reported.

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Detecting the presence of bacterial DNA by PCR can be useful in diagnosing culture-negative cases of infection, especially in patients with suspected infection and antibiotic therapy. The patient underwent a right functional endoscopic sinus surgery, where debridement of both right maxillary and ethmoid sinuses was done. The purpose of the present review is to briefly summarize the effects of major cytokines (leptin, adiponectin, tumor necrosis factor-alpha, and interleukin-6) on muscle metabolism and insulin response, with a focus on the effects of diet and exercise. Our objective was to assess the role of fusion positron emission tomography-computed tomography (PET-CT) in staging patients for minimally invasive oesophagectomy (MIO) with potentially resectable disease from the perspective of a multidisciplinary team (MDT) deciding on operability with conventional staging investigations. One of the main determining factors of success in renal transplantation is human leukocyte antigen (HLA) compatibility between donor and recipient, particularly at HLA-A, HLA-B and HLA-DR loci.

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This property explains the experimentally often observed spatial localization of the oscillations. First, the disease is largely a problem in elderly patients, who are likely to have comorbid conditions. A strategy employing moderate hypothermia for replacement of the aortic arch is proposed to avoid the complications of profound hypothermic circulatory arrest.

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SD rats were established to MI model by left anterior descending coronary artery (LAD) ligation. Laparoscopic bilateral uterine artery occlusion plus partial resection of symptomatic adenomyosis is effective.

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The human X chromosome is enriched for germline genes expressed in premeiotic germ cells of both sexes. This cross-sectional study was performed on 200 CAD patients who had undergone elective coronary angiography at the cardiology department. The use of a drug-coated balloon for native coronary vessel management is emerging as an alternative treatment, although in selected patient populations only. As it is not clear how to choose the weighting parameters, we use multi-objective optimization to calculate a set of Pareto-optimal RNA sequence-structure alignments. Patients with NRH are also not recommended to undergo routine screening for the development of HCC.

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The interaction of bone and glucose metabolism established by these studies will be important to a study of the two scientific fields in the future, particularly a clinical field. Genes with less than a 50-fold increase in expression: COL1A1, COL5A2, COL12A1 and COL17A1. The authors describe the occurrence of such a tumor in association with multiple intrahepatic cholesterol gallstones. Peripartum, the patient was continued on nitric oxide and subcutaneous enoxaparine. Buflomedil concentrations in blood and viscera in a case of fatal intoxication.

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In this chapter, we will describe the neurocircuitry involved, and will summarize evidence for adaptations in glutamatergic neuroplasticity as a mechanism for cocaine addiction. We show in this letter that the thermodynamic properties of helical peptides can be tuned by varying the degrees of backbone hydration. Spontaneous rupture of utero-ovarian vessels during pregnancy is a rare cause of maternal and fetal loss.

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What is not known is the associations and costs of parental psychiatric distress within a multi-diagnosis group of special needs children. This cluster-randomized clinical trial included patients from 4 primary care pediatric clinics.

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There were 748 NF-kappaB targets predicted and individually annotated for RELA, NFkappaB1 or cREL regulation, and a prevalence of RELA related genes was observed in over-expressed clusters in a tumor subset. Therefore, the avidin-biotin method appears to be appropriate for studies on HPA binding to detect altered glycoforms in cancer. Lens doses were measured using a planar silicon pin-photodiode system.

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We evaluated the findings from 17 patients with venous impotence. The increased expression of CXCL16 has been demonstrated in inflamed lesions of patients with Crohn disease. Solubilization and partial characterization of cell membrane Fc receptors. Characteristics and evaluation of volatile organic compounds discharge in typical enterprise wastewater in Hangzhou City Arginine metabolism was assessed by measuring the pH in the presence of glucose and arginine.

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CLR and RAMP1 were shown to be located in both vascular smooth muscle and endothelial cells of rat mesenteric arteries by immunohistochemistry. Current methodological limitations in the stress and gut inflammation research have made it difficult for us to ascertain the role of stress in inflammatory bowel disease. H1299 cells stably overexpressing Id3 were resistant to growth suppression and induction of cell death induced by the BMP antagonist DMH2. The difficulty in determining optimal therapy, owing to the sparse literature available, led us to present this case.

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A CO2 laser was considered to be a good alternative for the removal of melanocytic nevus in this area. Optogenetic activation or genetic blockade of this circuit reveals that it is both necessary and sufficient for rapidly increasing V1 cortical responses following manipulation of visual experience in adult mice.

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Fibromyalgia may have negative effects on sexual function in women. Findings were assembled and rated according to their quality, and categorized on the basis of similarity in meaning. This finding opens the way for the development of a family of recombinant viruses in which the profusion domain of gD and independently furnished, interacting receptor-binding domains effect entry of the virus via a range of receptors. Nevertheless, there is little knowledge on the usefulness of these biomarkers in evaluating the results of treatments targeting coronary artery disease.

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Intravital video imaging of Anopheles gambiae showed that, relative to sucrose fed mosquitoes, the deprivation of both sucrose and water for 24h, but not the deprivation of sucrose alone, reduces the heart contraction rate. X-ray of proximal femur is indicated in patients with long-term bisphosphonate use and non-traumatic hip/thigh pain.

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New TNF-alpha analogues: a powerful but less toxic biological tool against tumours. Thoracoscopy in the instance of delayed presentation may offer the best chance for minimal-access diagnosis and treatment when there is suspicion of a right-sided diaphragmatic rupture.

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Water-soluble narrow-line radicals for dynamic nuclear polarization. When the chemical stability of calreticulin was assessed, a midpoint for calreticulin unfolding was calculated to 3.0M urea using CD data at 222 nm. Thus, DNA methylation could be a major mechanism by which to produce semi-stable changes in gene expression in somatic tissues. The risk of bleeding and renal dysfunction appears to be increased in the elderly, though still within acceptable ranges compared to other full support devices. Despite 15 years of clinical research, the diagnostic value of TGT remains controversial, possibly due to suboptimal sensitivity to coagulation deficiencies, robustness and reproducibility.

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Slow potential fields generated in cerebellar cortex by mossy fiber valleys. After an injection of 2.0 mg/kg Althesin, heart rate (63 per cent) and cardiac output (21 per cent) increased, while total peripheral resistance (25 per cent), mean aortic pressure (9 per cent) and the maximum rate of change of left ventricular pressure (31 per cent) decreased. Laparoscopic ultrasonography, although still in a preliminary phase of development, is a simple and reliable technique that will contribute to more accurate staging of intra-abdominal malignancy. Furthermore, the full-thickness skin wounds on Wistar rats demonstrated that, compared with gauze and the top side of the BC film, the wound covered by the bottom side of the BC film showed faster recovery rate and less inflammatory response.

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The results obtained showed that aspirin esterase I from mouse liver and kidney had the lowest activity and that the activity of aspirin esterase II from these organs was greater than that from the same organs from rats. Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA. The Dirac nodes can be unbuckled through breaking the mirror symmetry and a photonic analog of Chern insulator can be achieved through time reversal symmetry breaking. From the histological point of view, thymoma and thymic carcinoma are the most frequent subtypes and arise only from thymic epithelial cells.

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The results suggest that pitch perception does not arise through spectral processing in nonhuman mammals but rather through temporal processing. Yet, brain death has not been established as a clear clinical or pathologic entity, a point brought out here by comparison of criteria for identification. Type 2 diabetes after gestational diabetes mellitus in South Asian women in the United States. Central vein leads are known to predispose to venous obstruction.

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We aimed to assess the changes in muscle strength, muscle function, postural stability, quality of life (QoL), and well-being during treatment with vitamin D or placebo before and after parathyroidectomy (PTX) in PHPT patients. Our study improved upon most previous studies by having a longer follow-up period, a larger sample size of long-term SSRI users and consideration of risk during specific exposure time windows that take latency into account. As we examine each of these relationships, we consider theoretical models that might shine a light on the observed association between rate of molecular evolution and diversification rate, and critically evaluate the empirical evidence for these links, focusing on phylogenetic comparative studies.

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The relationship between Cmax and AUC was not linear but concave. Unsurprisingly, variability of excipients has been well researched within specific focus areas. All patients received approximately 1 mg/kg meperidine (up to 50 mg) intravenously.

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None of the other cytokines evaluated (IL-1 beta, IL-3, IL-4, IL-5, and IL-11) were detected in supernatants or lysates of resting or stimulated cells. Funders and accreditation standards increasingly call on state and local public health agencies to use the best available science. Despite the positive influence of spiritual coping on the acceptance of a cancer diagnosis, higher spirituality is associated with receipt of more high intensity care at the end of life. Scores on the Opinion, Attitude, and Interest Survey made by freshmen who later successfully completed work in the Physical Therapy Curriculum at the University of Michigan were compared with scores of eighteen other freshmen groups at the university. Analysis of action plans and coping plans for reducing salt consumption among women with hypertension.

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Stratification of Archaea in the deep sediments of a freshwater meromictic lake: vertical shift from methanogenic to uncultured archaeal lineages. Computer navigation of the acetabular component: a cadaver reliability study.

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Chemotherapy and radiation therapy have had little impact on survival, prompting the National Cancer Institute to declare that survival for pancreatic cancer has remained unchanged for three decades and its treatment has consistently been identified as an area of unmet medical need. Analysis on oil fume particles in catering industry cooking emission Decreased infection may be possible with fully implantable LVADs such as the LionHeart, which lacks percutaneous conduits (PCs), a common source of device-related infection (DRI). We describe the use of twin dorsal middle finger flaps harvested from the dorsal aspects of the middle and ring fingers, and based on one palmar proper digital artery, its venae comitantes, and the dorsal branches of the palmar digital nerves of the middle and ring fingers, respectively. Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model.

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International Czech and Slovak cooperation in the treatment of patients with differentiated thyroid cancer. Comprehensive analysis of NAC domain transcription factor gene family in Vitis vinifera. 2005, 127, 4888-4894), on the basis of photochemical and photophysical experiments. Decreased IL15 expression affected the local proliferation of B and T lymphocytes. Comparative, cross-sectional, retrospective, demographic survey with 1-year follow-up.

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The immune response reactivity was proved to be the case immediately before the physiological labour and in premature delivery. Budd-Chiari syndrome with hepatic vein occlusion (HVBCS) can induce severe portal hypertension and liver damage. It measures the infrared absorption in each individual gas peak after separation by the GC column, and maintains the shapes of gas peaks after the HWIR sensor, making the gas samples further available for other sensors. Myeloablative conditioning regimens before allogeneic stem cell transplantation are being replaced with concurrent autologous-transplantation and reduced-intensity conditioning allogeneic stem cell transplantation.

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TGF-beta s are secreted from cells in high-molecular-mass protein complexes that are composed of three proteins, the mature TGF-beta-dimer, the TGF-beta propeptide dimer, or latency-associated protein (LAP), and the latent TGF-beta binding protein (LTBP). The use of tungsten disulfide dots as highly selective, fluorescent probes for analysis of nitrofurazone.

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Primary health care for lek contix 20 mg pre-school children in Croatia is provided by the primary pediatricians (PPs) in urban, or family doctors (FDs) in rural areas. These results, the first study of HIV-infected adults to directly compare verbal versus spatial working memory performance using the identical test stimuli across task conditions, suggests that HIV infection is associated with a decrement in working memory efficiency that is equally apparent for both verbal and spatial processing.

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Electron transfer quenching in light adapted and mutant forms of the AppA BLUF domain. We observe significant base-dependent features in the LDOS in an energy range within a few electronvolts of the Fermi level. Our approach mimics and manifests induced fit in molecular recognition. Use of epsilon-aminocapromic acid aspirin vs clopidogrel cost effectiveness in the treatment of vasomotor rhinitis

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Fluid intake history for previous seven days, and standardized psychological and behavioural measures of eating disorders, mood, personality and health, were completed on admission to hospital. These results suggest that the sustained LV delivery system from PUR scaffolds is a potentially safe and effective device for bone regeneration. To estimate the proportion of potential soft contact lens wearers requiring an astigmatic correction and to estimate the proportion of astigmats who can be accommodated with toric soft lenses of pierre marchais vicard medicine varying prescription range.

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