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Effects of diesel exhaust inhalation on heart rate variability in human volunteers. All PN patients at the Princess Elizabeth Hospital in Guernsey during a 1 year period (November 2006-December 2007) were subject to audit.

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An in vitro and in vivo evaluation of a reporter gene/probe system hERL/(18)F-FES. Introgression was bi-directional and both hybrid zones consisted mostly of parental genotypes/phenotypes (i.e.

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Mutation Update of ARSA and PSAP Genes Causing Metachromatic Leukodystrophy. To describe the epidemiology, clinical features and risk factors associated with an outbreak that occurred at a vocational boarding school in Guangzhou, P.R.

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A patient with moderately severe mucous membrane pemphigoid is described. The gender differences in the genome were studied by RAPD which was optimized by the single factor and orthogonal experiments. Medical students and the Affordable Care Act: uninformed and undecided.

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Amphetamine exposure or activation of protein kinase C (PKC) by the phorbol ester PMA has been shown to down-regulate cell surface DAT. We compared the results of 792 consecutive gynecological frozen section diagnoses with their final diagnoses from January 1991 to June 1996. The schedule for the fifth group was changed to multiple variable-interval 1-min extinction schedule of reinforcement. Several genes have been implicated as influencing the outcome following traumatic brain injury (TBI).

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The transport of amino acids across the placenta is a complex process that includes the influx of neutral, anionic, and cationic amino acids across the microvilluos plasma membrane of the syncytiotrophoblast, the passage through the cytoplasm of the trophoblasts, and the transfer outside the trophoblasts across the basal membrane into the fetal circulation. Scientific quality not only depends on citation scores, but also on originality, societal and scientific impact, robust methodology and validity and should therefore be evaluated on these parameters. The aim of this study was to determine the highest cited papers published in Neurology India and analyze their attributes.

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The use of guided tissue regeneration to improve implant osseointegration. Wt L1 and L2 but not mutant L1 proteins and wt L2 efficiently encapsidated DNA and transferred it into cells, suggesting that physical interaction of L1 with DNA is essential for DNA inclusion into VLPs.

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Two categories of diabetes are recognized in the temperate zone--ketosis-prone diabetes requiring insulin and diabetes not requiring insulin. However, to date, gene-targeted mammalian models of human genetic disease have not been reported for any species other than mice. This method has proven highly efficient in transferring, in particular, plasmid DNA to muscles, resulting in long-term expression of the transferred genes.

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Scanning electron microscopy (SEM) and morphometric procedures designed to survey large areas of intraparenchymal vasculature disclosed the widespread production of cerebral endothelial microvilli following global ischemia of the rat forebrain. Costimulation through CD3 plus ICAM-1 caused increased T cell proliferation, increased expression of the activation marker CD69, increased transcription through the IL-2 regulatory region, and increased secretion of selected Th1 but not Th2 cytokines. Moreover, overexpressed samples displayed 17-fold pSer(318)-Atg13 above wild type levels of with no apparent differences in compound potency. Methods of obtaining chromatographically pure glycerolipids, their subfractionation, and the quantitative analysis of glycerolipids are described.

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Untargeted next-generation sequencing-based first-line diagnosis of infection in immunocompromised adults: a multicentre, blinded, prospective study. Using Siglec-G x CD22 double-deficient mice, we addressed whether Siglec-G and CD22 have redundant functions. Poly (3, 4-ethylenedioxythiophene) doped with poly (styrenesulfonate) (PEDOT/PSS) is coated on the surface of flexible MNA to form a conductive layer. Enlightment of the population in general on blindness and its prevention.

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SodB may be useful as a constituent of vaccines for control of C. However, common myths that may affect care include: 1) NA patients will not discuss death and dying, 2) severely ill NA patients and families will not choose do not resuscitate (DNR) status, and 3) NA patients and families will not utilize hospice services if offered. More than half of the anastomotic leaks were associated with either severe sepsis or death. Sequencing of polymerase chain reaction products suggested that alterations in the HBsAg transgene in HBsAg-negative foci occurred via large-scale deletions as opposed to single-site mutations. In addition, a rate-matrix approach to calculate distances from etNOESY intensities using a volume matrix comprising only intraligand intensities was found to give accurate values.

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Rapid diagnosis of sickle cell disease at birth by microcolumn chromatography. It has been shown that virus accumulation and formation of virus-specific cylindrical inclusions (CIs) occur in the infected cells, in addition to intracellular changes showing stimulation of lytic processes, such as activation of smooth endoplasmic reticulum and Golgi apparatus, formation of cytoplasmic vacuoles, cytosegresomes, myelin-like bodies, different disturbances in the structure of cell organelles. While single parameter estimation theory has been widely investigated, much less is known about the simultaneous estimation of multiple phases, which finds key applications in imaging and sensing.

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The downstream side of gp130 consists of two distinct pathways in cardiac myocytes, one a Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway, the other a mitogen-activated protein kinase (MAPK) pathway. The hearing threshold increased after noise exposure and recovered to normal within 5 days in all groups. Postinjection voice is significantly improved, and the majority of patients do not experience breathy voice/decline in vocal function after injection.

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Results of an investigation of the effects of a complex of gamma globulins and histamine in allergic therapy of children Inhomogeneous and complementary antegrade and retrograde delivery of cardioplegic solution in the absence of coronary artery obstruction. Thirteen of 45 cases of congenital anomalies of the lumbosacral nerve roots at their site of emergency (ARE) were treated surgically. Probing cortical excitability using cross-frequency coupling in intracranial EEG recordings: a new method for seizure prediction.

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How and why spermatozoa cause calcium oscillations in mammalian oocytes. There was observed an improvement of ALAT and ASAT, normalization of the fasting blood glucose, and increased sensitivity to exogenous insulin.

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There is no doubt that the future of guideline implementation will strongly depend on the development of easy to use decision support algorithms tailored to the individual patient and on evaluating the effect of guideline implementation on surgical outcome. This paper reviews in brief the epidemiology, clinical features, diagnosis, molecular pathogenesis, and specific therapies of patients classified by AERD and postulates future attempts to gain new insights into this disease. The clinical bottom line is that in patients with cocaine induced chest pain it appears that nitrates or benzodiazepines are effective in combination or alone in resolving chest pain and improving cardiac performance.

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A 72-year-old postmenopausal woman with high plasma testosterone levels and virilization, as demonstrated by hirsutism and balding, is presented. Its presence in a range of sample types, any of which could be submitted under BSE and scrapie surveillance programmes, confirmed it as a suitable protein for an IPC marker in PrP(Sc) Western blotting. Citric, orotic, and other organic acids in rats injected with active or inactive urease. Recent studies provide evidence that nitric oxide (NO) has beneficial effects in hepatic ischemia/reperfusion injury. The brains of the control and CL fish were larger at 4 dpf than at 8 dpf.

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All NHS trusts in England, Wales Northern Ireland and Channel Islands were eligible to participate. Site-directed mutagenesis of the yeast multicopper oxidase Fet3p. The SCI women reported that the injury caused many changes in their sex life and affected many aspects of their sexuality negatively.

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Acute cervicitis and vulvovaginitis may be associated with Cytomegalovirus. Importantly, surface-enhanced Raman spectroscopy (SERS) effects are observed without the presence of any metal surface in the system. The results showed a virtual 100 per cent accuracy of diagnosis between pregnancy and non-pregnancy and approximately 70 per cent overall accuracy in differentiating single from multiple pregnancies. Speech tasks were scored for percentage of phonemes correctly produced. Heart failure (HF) is mainly detected and managed in primary care, but the care is considered suboptimal.

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Students perspective on the impact of gender on medical training and future practice. Metabonomic analysis showed differences between sham control and coronary artery ligated hearts particularly with respect to preservation of myocardial taurine levels. Studies on factors which increase peripheral glucose uptake in man. Patients with high postoperative CEA levels may benefit from adjuvant chemotherapy. In this paper we systematically study this approach in a large variety of dilute colloidal systems composed of spherical and nonspherical hard particles, in two and in three dimensions, in the bulk and in front of a hard wall with a relief pattern.

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Spectroscopic study on the binding of porphyrins to (G(4)T(4)G(4))4 parallel G-quadruplex. Small-for-size syndrome remains the greatest limiting factor of expanding segmental liver transplantation from living donors. The plasma membrane (PM) regulates diverse processes essential to plant growth, development, and survival in an ever-changing environment.

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Mandated nurse staffing ratios in California: a comparison of staffing and nursing-sensitive outcomes pre- and postregulation. Cerebral coenurosis in a cat caused by Taenia serialis: neurological, magnetic resonance imaging and pathological features. The mechanisms of action of isoflavones have been diverse and include their roles as weak estrogens, inhibitors of tyrosine kinase-dependent signal transduction processes and as antioxidants.

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We perform a novel method in this study for the expression and purification of recombinant PEDF34 in E. A novel and efficient method for the regioselective nitration of a series of aliphatic and aromatic carboxylic acids to their corresponding nitro compounds using nitronium tetrafluoroborate and silver carbonate in dimethylacetamide has been described. These findings have practical implications when assessing cardiac enlargement and function in physically active youngsters.

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Effect of oxythiamine on the thiamine phosphorylation by the thiamine pyrophosphokinase of yeast. The model was parameterised using empirical and population-based data for 20 countries in SSA. The hospital infection control computer database was used to identify patients who had a CA-MRSA infection with organisms isolated from blood, bronchoalveolar lavage fluid, or pleural fluid samples. Urinary cystathionine, urinary 4-pyridoxic acid, plasma phosphate, erythrocyte alanine, and aspartate aminotransferases were not significantly changed.

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These results revealed that CdA induces caspase-independent apoptosis in DC and suggest cell type specific effects of CdA. To evaluate a newly developed rapid whole blood test in coeliac disease antibody detection, and its suitability for office use. Good visual recovery was obtained early by LM with a stable outcome at 6 months. The resulting extensive dural opening allowed complete evacuation of the subdural hematoma.

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The methods have been illustrated with a numerical example using Markov-chain Monte Carlo (MCMC) techniques. The City Infant Faces Database: A validated set of infant facial expressions. Distearoylphosphatidylcholine/cholesterol liposomes were formulated using buffers containing various copper or manganese concentrations, and irinotecan loading was determined in the presence and absence of divalent metal ionophore A23187. Field tests were performed for several hours on a single filter element at about 550 degrees C.

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Factors assessed at the time of program enrolment were predictive of later dropout and should be further studied to provide information for future program improvements. In some, dysplastic changes in these polyps have also been reported. Chromosome polymorphism was associated only with B chromosomes that were revealed in all studied populations. International organisations emphasise the importance of improving pain assessment.

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The change of prostatic volume was measured frequently by transrectal ultrasonography (TRS) after castration, as was the change of PSA. Hyperglycemic pseudorejection in the diabetic transplant patient.

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The threat of bioterrorism has led to increased concerns over the availability of biological select agents and toxins (BSAT). In particular chrysin and kaempferol significantly synergised in their inhibitory effect upon NO, PGE(2) and TNF-alpha secretion. The inflammation-responsive IkappaB kinase (IKK)-beta and its target NF-kappaB have important tumour-promoting functions within malignant cells and inflammatory cells. HRpQCT and FEA showed that at the distal radius, Blacks had greater cortical perimeter, cortical area, trabecular thickness, trabecular BMD, estimated failure load, and stiffness than the other two groups.

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Neither the chemical determination of bilirubin in amniotic fluid nor the lecithin/sphingomyelin ratio as determined by thin-layer chromatography is affected by these glucocorticoids. Either Fe2O3 or CoO NPs were grown onto rGO sheets in ethanol solution through a solvothermal process, during which GOs were reduced to rGO without the addition of any strong reducing agent, e.g. Together these results highlight an important role for p21 and p/CAF in promoting breast cancer cell migration and invasion at the transcriptional level and may open new avenues for breast cancer therapy.

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Locomotor activity was increased by scopolamine and oxotremorine-M administration in all treatments. They are becoming widely accepted by surgeons working in district hospitals, which was significantly contributed to by the publication of the EHS Guidelines on the Treatment of Inguinal Hernia. Axonin-1/TAG-1 was shown to promote neurite outgrowth in vitro and to be required for commissural and sensory axon pathfinding in vivo.

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In the present study, we investigated whether the TSH/Dio2/Dio3 signalling pathway of female common voles (Microtus arvalis) shows a similar degree of photoperiodic sensitivity to that described in other seasonal mammal species. Prevalence of Leptotrombidium deliense, the scrub typhus vector, in the eastern Himalayas. Macrophage-derived chemokine CCL22 and regulatory T cells in ovarian cancer patients. It is assumed that beside alterations in the filaggrin gene (FLG), disturbances within genes encoding other cornified envelope proteins are also involved in atopic dermatitis (AD). Practical syntheses of mono- and bis-aminooxy tetraalkylammonium iodides including N-hydroxyethyl-functionalized analogs are reported.