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High-energy deformation of filaments with internal structure and localized torque-induced melting of DNA. Persons currently enrolled in weight loss programs or with a body mass index (BMI) of less than 18.5 were dropped from the analyses, leaving 341 females and 153 males for analysis, with an average BMI of 27.4.

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The effects of acute subcutaneous (dose range 0.03-10.0 mg/kg) and chronic oral administration (2.0 mg/kg/day in drinking water) of cotinine were evaluated in fixed and variable stimulus duration (VSD) as well as variable intertrial interval (VITI) versions of a five choice serial reaction time task (5C-SRTT). MYD88 L265P mutations were found in 11/11 LPL cases versus only 2 of 28 other SBLs included in its differential diagnosis. Thirty-five amnestic MCI patients and 121 healthy aging controls enrolled at an Alzheimer Disease Center received a battery of standard neuropsychologic tests, and the Semantic Object Retrieval Test (SORT), a test that we have developed for the assessment of semantic memory and subsequent name production, and that has been shown to be able to differentiate between normals and patients with AD.

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The primary end point was first-attempt success rate for IV catheter placement. Oxides and their precursors have been extensively studied, either singly or in combination with other amendments promoting sorption, for in situ stabilization of metals and As in contaminated soils. Dimensional assessments are planned to be included as supplements to categorical diagnoses in DSM-V. It focuses on fetal brain imaged in vivo and in utero with complementary sections on abnormalities seen in clinical settings, and on potential of diffusion tensor imaging and of proton magnetic resonance spectroscopy. The MMPs and their specific tissue inhibitor metalloproteinases (TIMP) have been associated with tumor cell invasion and metastasis in a number of adult tumors.

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However, the morphology of fibrocytes and their interactions with parasites are poorly understood. The preliminary follow-up of fifty-four metacarpo-phalangeal joint replacements showed thirty-five good and sixteen fair results. These results strongly suggest that RASSF1A is an important human tumor suppressor protein acting at the level of G(1)/S-phase cell cycle progression. A three-dimensional chemo-mechanical continuum model for smooth muscle contraction.

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Undifferentiated carcinoma of the pancreas: analysis of intermediate filament profile and Ki-ras mutations provides evidence of a ductal origin. The effects of rhodamine 123 on the cell growth of the cultured cells derived from urogenital carcinoma

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New technology from Roche Applied Science enables continuous monitoring of cells in real-time using specialized culture dishes containing micro-electrodes. Lactate dehydrogenase isoenzyme in detecting carriers of Duchenne muscular dystrophy.

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There were no differences in toxicity between the two vectors when measured at matching levels of hAAT expression. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Ideals and primitive elements of some relatively free Lie algebras.

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Spectroscopic and electrochemical characterization of nanostructured optically transparent carbon electrodes. Efficacy of IV systemic thrombolysis is limited in patients with severe acute ischemic stroke and large-vessel occlusion. The relationship between intrathecal clonidine and hypertension was investigated in SHR rat and WKY rat. Treatment was started orally before chemotherapy and continued for 3 months after the suspension of cisplatin. We also show that the TIMMA-R predictions are robust to the intrinsic noise in the experimental data, thus making it a promising high-throughput tool to prioritize drug combinations in various cancer types for follow-up experimentation or clinical applications.

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Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion. Several case reports describe spinal capillary hemangiomas in adults, but only one found in the literature describes a case in an infant.

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The purified CoF had 1 unit of functional anticomplementary activity per 1--2 micrograms of protein, and was homogeneous on gradient and non-reduced sodium dodecyl sulphate (SDS) polyacrylamide gel electrophoresis (PAGE). This paper captures the implications of this poor sensitivity for the interpretation of studies of outcome that compare provider performance, and considers in what circumstances monitoring outcome might be useful. To examine the effects of parenting distractions on supervising behaviors in relation to child risky behaviors.

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A measuring unit based on fiber Bragg grating (FBG) for fluid temperature and a unit for heat dissipation are designed to replace the traditional electronic sensors. This design is demonstrated for detection of caspase-8 activation. We present a systematic analysis of sequence motifs found in metazoan protein factors involved in constitutive pre-mRNA splicing and in alternative splicing regulation. The screening identified an organoselenium compound which scavenged H2O2 more effectively than the vitamin E analog, Trolox.

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The high angular momentum limit shows localization of electrons and separation of the charge and spin excitations. Validation of a teamwork perceptions measure to increase patient safety. The difference between the two kinds of markers can be explained by differences in their mode of inheritance, the mtDNA being maternally inherited in contrast to nuclear loci that are bi-parentally inherited.

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We report these two cases and discuss the effects of spinal anaesthesia on thermoregulatory system. Using two-dimensional difference gel electrophoresis in combination with LC-MS/MS, we observed significant abundance changes in 15 protein spots. CHS is an underappreciated cause of recurrent nausea and vomiting and is frequently misdiagnosed.

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Blocking the 12-LOX gene expression with sequence-specific antisense oligos or its activity with general or isoform-specific LOX inhibitors induces a strong apoptotic response in rat W256 carcinosarcoma cells of the monocytoid origin (Tang et al., 1996, Proc. Thermodynamic characterization of the complete set of sequence symmetric tandem mismatches in RNA and an improved model for predicting the free energy contribution of sequence asymmetric tandem mismatches. In most cases they are accompanied with numerous microscopic or macroscopic nonfunctioning P-NETs, which are potentially metastatic and the most common cause of death in MEN 1 patients. Both spectrophotometric and radioactive assay procedures demonstrated a lack of significant citrate synthase activity in the dialysed extract of the mutant compared to the wild type strain.

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Therefore, a multidisciplinary approach can lead to diagnosis and to an appropriate treatment in most of the cases. As negative regulation of orthologs of these ARFs by ta-siRNA is common to land plants, we propose that ta-siRNA levels serve as universal sensors for interference with small RNA biogenesis, and changes in their levels direct species-specific responses.

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However, their therapeutic benefit is offset by serious side-effects, primarily gastrointestinal and cardiovascular complications. It was also found that from the molecular excitation point of view not only the magnitude of the transition dipoles between the involved orbitals but also their orientation with respect to the laser field is important. Achromatic imaging of distant objects in selected wavelength bands with plane and concave holographic gratings. On the other hand, the sensitivity to ethanol was decreased in the cerebellar Purkinje neurons.

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Thus, the present approach is a novel way of producing porous materials as the particle size of the template could be changed and templates become hard when they were molded as compared to the conventional methods in which there is no change in phase for the templates under 100 degrees C. Increased population prevalence of reflux and obesity in the United Kingdom compared with Sweden: a potential explanation for the difference in incidence of esophageal adenocarcinoma.

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Salvage of major amputation stumps of the lower extremity with latissimus dorsi free flaps. Several varieties of fluid warmers are available to help prevent hypothermia. Children with schizophrenia-spectrum disorders: thought disorder and communication problems in a family interactional context. The karyotype of the parental clones, cell hybrids and polyploids was analyzed in parallel. When imatinib-resistant cells were transfected with the facilitator PNA and DNAzyme, DNAzyme activity was enhanced and the cells were sensitized to imatinib treatment.

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This study clarifies the type and number of symptoms that best predict premenstrual impairment in a sample of women undergoing prospective assessment for premenstrual dysphoric disorder (PMDD) in a research setting. Efficacy within the dose range of 40-120 mg/d was established in four 6-week, randomized, controlled trials. Therefore, it is necessary to amplify this reflection by workers of the Family Health Strategy, aiming to encourage the minimization of suffering experiences, considering their ethical values.

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Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2. By subsequent bacteriological examination Salmonella abortusequi was isolated as the single causative agent in each case. Cortical regions were automatically parcellated from high-resolution structural images, and HARDI-based connection matrices were produced for statistical comparison. The FVL mutation is an important factor in the pathogenesis of BCS and screening for the disorder must be included in the investigation of patients presenting with this condition.

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Small bowel diagnostics should be carried out if the aetiology of an anemia is not certain with an existing polyposis of the colon. Detection of two different influenza A viruses using a nitrocellulose membrane and a magnetic biosensor. Wave speed is directly related to arterial distensibility and is widely used by clinicians to assess arterial stiffness. Similarity of gene expression profiles provides important clues for understanding the biological functions of genes, biological processes and metabolic pathways related to genes. Senior citizens are at an increased risk of developing chronic conditions, which in turn increase discomfort associated with physiological processes of aging.

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Dectin-1 expressed in corneal epithelium of normal persons and FK patients. In particular, we demonstrate that combining the typical NMR software with artificial intelligence-based prediction of secondary structure enhances significantly the accuracy of the restraints for molecular modeling. Ultrasonogram-guided needle biopsy from the liver tumor showed diffuse infiltration of CD20 positive, small lymphocytes.

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Parent-child correlations and heritability estimates are moderate to high for both traits, but aspects of the family environment remain influential in young children, although no longer in young adults. The effect of experimental osteomyelitis on the endochondral growth of bones in length Reduced circulating levels of angiotensin-(1--7) in systemic sclerosis: a new pathway in the dysregulation of endothelial-dependent vascular tone control. Both agents killed cancer cell lines in vitro with similar IC(50) values and with apparently similar cytotoxic mechanisms as unconjugated doxorubicin and etoposide.

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Intestinal metabolism of phenacetin in the rat: effect of charcoal-broiled beef and rat chow. Low-dose chemotherapy has been used for unresectable cancer as a tumor dormancy therapy, and it has been reported that the patients treated this way demonstrated favorable survival without toxicity. The role of environmental conditions on driving beetle outbreaks is becoming increasingly important as global climatic change alters environmental factors, such as drought stress, that, in turn, govern tree resistance.

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It points out the need for continuous clinical evaluation to detect their appearance. These results suggest a role for SPARC in the process of angiogenesis following injury to the adult cerebral cortex. In five conditions, the absolute (and equal) reinforcement rates provided by the pair of equal-valued schedules were manipulated in the range of 36 to 240 per hour.

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It may be concluded that during pulmonary gas embolism the administered gas is excreted into the alveolar air and that the excretion rate largely depends on the increased pulmonary arterial pressure due to the obstructing bubbles themselves. The role of chromatin-modifying factors in cancer biology emerged exponentially in the last 10 years, and increased attention has been focused on Polycomb group (PcG) proteins and their enzymatic activities. Here, we show that AQP3, which has been incriminated in cancer progression, is regulated by the AhR, or dioxin receptor.

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The findings and implications were discussed in relation to developmental and migration-related issues and the social contexts of the lives of children of migrant workers in Shanghai, China. The A549 alveolar type II epithelial-like cell culture model was used to demonstrate that alveolar type II cells constitutively express CCR5 which may be upregulated by MIP-1alpha (CCL3) whose expression was induced by the Th1 cytokines IL-1beta and IFN-gamma. CNTF receptor alpha was stronger in control extensor digitorum longus (EDL) than soleus. Appropriate hemostasis is essential for clear visualization of the neural structures and cleavage planes.

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Taxanes should not be excluded, if indicated, in pregnant patients with cancer. The prevalence of traumatic dental injuries to permanent anterior teeth and its relation with predisposing risk factors among 8-13 years school children of Vadodara city: an epidemiological study. To determine whether there is a relationship between the presumed complexity of auditory processing and the time course of recovery of auditory function in children with a history of otitis media with effusion (OME).

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A cationic colloidal iron method was introduced for electron microscopic detection of anionic sites in hydrophilic resin-embedded specimens, and the method was applied to Paneth cells of the mouse jejunum. Cell differentiation modeled via a coupled two-switch regulatory network. 225 policies were investigated by using convenience sampling and cluster sampling methods, occupational stressors, strains, buffer factors and individual factors were measured by questionnaires. We detected expression of ODC in breast cancer tissues and four breast cancer cell lines, and transfected breast cancer cells with an adenoviral vector carrying antisense ODC (rAd-ODC/Ex3as) and examined their growth and migration. The use of the nursing process can lead to improved health of populations.

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The objective is to review the evidence for the effectiveness of health communication campaigns to inform future nutrition campaigns. Thus age-prevalence data, which is relatively easy to gather in clinical or agricultural settings, can be used to evaluate contact patterns and infer the likely age-cohort responsible for transmission of directly transmitted infections.

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Non-contaminated samples from core sediments were selected according to the sedimentation rate, 32 types of profile pattern based on metal concentrations and metal/Cs ratios, and their variability in past sediments. After stenting patients exhibited dramatic improvement in their respiratory symptoms and quality of life. PfAARP2 is first expressed 12 h post-invasion and accumulates in trophozoites and schizonts. Stroke after piercing barbed wire injury: a time for introspection. Tartrate resistant acid phosphatase (TRAP) is an enzyme expressed by subsets of macrophages and osteoclasts that exists either as an enzymatically inactive monomer or as an active, proteolytically processed dimer.