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More than thirty Rab GTP-binding proteins are known to function in diverse membrane transport pathways, although their mechanisms of action are unclear. Clinical observations on 23 cases of human rabies and considerations on its prevention Prevalence of livestock diseases and their impact on livelihoods in Central Equatoria State, Southern Sudan.

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Longitudinal change in aphakic refraction after early surgery for congenital cataract. Megafaunal fruits allow plants to circumvent the trade-off between seed size and dispersal by relying on frugivores able to disperse enormous seed loads over long-distances. To evaluate whether there were differences in acquisition of research grant support between male and female faculty at eight Harvard Medical School-affiliated institutions. In lesional psoriatic skin, the p38 MAPK negative feedback mechanism provided by DUSP1 seems to be inhibited.

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Lipases are the most used enzymes in synthetic organic chemistry, catalyzing the hydrolysis of carboxylic acid esters in aqueous medium or the reverse reaction in organic solvents. Feasibility and acceptability of a Tai Chi Chih randomized controlled trial in senior female cancer survivors. Laboratory procedures are already largely harmonized but information on the sampled animals is not systematically collected. The establishment of assessment reliability at the level of the individual trainee is an important attribute of assessment methodologies, particularly for doctors who have been failed. In data from the United Kingdom Clinical Practice Research Datalink, all women who were newly treated with antipsychotics from 1990-2013 were identified and followed until 2014.

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Support for a developmental hierarchy has only been inferred from the memory performance of adults with amnesia on priming and recognition-recall tests in response to manipulations of different independent variables. Bucco-dental accidents and the appropriate therapeutic indications for diabetic patients Large and complex bone defects or voids cannot rely on natural bone healing process for recovery.

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Treatment of irreparable radial head fractures with a modular titanium radial head prosthesis and soft-tissue reconstruction yields satisfactory results. Laboratory investigations indicate a clear-cut correlation between immunological alterations induced by HIV infection and its neurologic manifestation on ascending sensory tracts. Seventy five percent of the children found CBC scale to be the easiest among the three scales. Furthermore, in vitro kinase assays revealed that STAT5 is a direct target of Flt3.

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Nutritional modulation of the gut microbiota and immune system in preterm neonates susceptible to necrotizing enterocolitis. Using a transgenic mouse system in which an activated erbB-2 is overexpressed in the epidermis, we show that ILK expression is regulated by erbB-2. Clinical criteria for diagnosis of migraine-associated otalgia are suggested for future prospective study.

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A point mutation of the androgen receptor gene affecting two siblings with partial androgen insensitivity syndrome is described. The ability of phage T4 to produce a fraction of virions unable to infect starved cells is linked to the functions of genes rI and rIII, as well as rIIA. The column assay demonstrates a broad linear range with low variability. Among children with parasitaemia at the end of the transmission seasons, the CVIET haplotypes of pfcrt and the 86Y polymorphism of pfmdr1 were more common among those that had received SMC, but the number of infections detected was very low and confidence intervals were wide. On the other hand, type II collagen expression and Alcian blue staining, both of which are markers of the early stage of chondrocyte differentiation, were similar in both cells.

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The BOOMER consists of timed static stance feet together eyes closed, Functional Reach, step test, and the Timed Up and Go test. Targeted ultrasound contrast agents, with a diameter on the order of micrometers, cannot extravasate and therefore are targeted solely to receptors expressed by the vascular endothelium. The identification of new biomarkers allowing noninvasive diagnosis and monitoring of disease activity would be advantageous. Ribozymes, catalytic RNA molecules that cleave a complementary mRNA sequence, have potential as therapeutics for dominantly inherited disease.

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These three proteins are allergens in wasp venom-sensitive persons. In addition, we observed that a stronger leftward asymmetry near the posterior intraparietal sulcus was positively associated with the number of meditation practice years.

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The depsipeptide structures of ramoplanins are synthesized by non-ribosomal peptide synthetases (NRPS). These studies support the potential suitability of salmon fibrin glue for the development of preparations with clinical impact. Given compactness and the relevant class of models, the theorem can be seen as showing that some measurements on composite systems must have built-in inefficiencies, complicating its testing. A significant association was detected between 2 SNPs analyzed in TNFA (-308 and -238) and atopic asthma and severe-persistent asthma.

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After the Fragilariopsis lineage acquired the antifreeze protein gene from the basidiomycetes, it duplicated and went through episodic evolution, characterized by strong positive selection acting on short segments of the branches in the tree. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene. Plasma rIL-2 levels were sustained longer in mice given the immune complex than in mice given rIL-2 alone at a dose of 10 micrograms/mouse, and they were detectable even at 24 hours after the administration of the immune complex, while they fell to undetectable levels by 6 hours after the administration of rIL-2 alone.

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Electrophysiological and behavioral effects of Tyr-D-Arg-Phe-Sar on locus coeruleus neurons of the rat. Moreover, the mutant spores did not become completely dark, as compared with the wild type strain. PTSD, Orientation to Pain, and Pain Perception in Ex-prisoners of War who Underwent Torture. Its use eliminates many errors inherent in previous methods of volume computation.

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This often results in an unacceptable performance of the filter. Assessment of isoflavonoid concentrations in Australian bovine milk samples. When concatenated into a construct of alternating I27 domains, Im9 unfolded below the thermal noise limit of the instrument ( approximately 20 pN). Adverse reactions included fever, general fatigue, leukopenia and thrombocytopenia, and abnormal liver function tests were experienced. The stimulation of DNA adduct formation correlated with the potential of 3-NBA to induce protein expression and activity of CYP1A1.

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The incidence of latex allergy in general pediatric surgical patients, however, has not been previously addressed. In the present study, we report the lesions of brain capillaries, including the choroid plexus, produced by chronic cocaine administration, in adult Wistar rats receiving i.p., 30 mg/kg/day of aqueous cocaine hydrochloride solution. In this review, we discuss the evidence for stem cells in NSCLC, their predictive and prognostic significance, their specific mechanisms of resistance and potential targets and strategies for eradication of these cells.

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With a deeper understanding of benign fibro-osseous lesions, clinicians will be better prepared to manage these lesions in their practice. In our patient, the biochemical findings were normal, except for hyperphosphatemia and elevated alkaline phosphatase.

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The aim of the present study was to investigate whether our optimal culture condition (OC) can maintain the phenotype of primary hepatocytes in long-term culture. Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a widespread indicator of severe oxidative damage and disease-derived protein dysfunction.

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Variations in inflammatory markers in acute myocardial infarction: a longitudinal study. Determination of the extent of such derangement in steady state type 2 diabetic patients enhances management planning and prevents diabetic complications. Herein, we report a case of a 76-year-old male patient who came with a complaint of deviation of his jaws to one side which revealed resorption of total part of the condyle along with the condylar head and coronoid process on radiographic evaluation, which was histopathologically diagnosed as primary intraosseous carcinoma which is a very rare clinical entity.

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In addition to magnetic resonance imaging (MRI) and compute tomography, DTI may be useful in understanding pathophysiology of spinal cord in earlier stages of the CSM but it may be confounded by age and cervical level, and previous studies had small sample sizes. Feeding rates, as all biological rates, depend on consumer and resource body masses and environmental temperature. Middle fossa approach for total resection of petrous apex cholesterol granulomas: use of vascularized galeofascial flap preventing recurrence. Increased serum lactate at maximum claudication subsequently declined despite continued improvement in walking distance, suggesting local adaptations to improve efficiency of muscle oxygen delivery and/or utilization. Bovine Serum Albumin Adsorption on TiO2 Colloids: The Effect of Particle Agglomeration and Surface Composition.

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A cosmid subclone (74A) contained a (GA)38 microsatellite motif, and hybridization with a (GA) oligonucleotide revealed that most of the hybridization sites of 74A correspond to the distribution of this microsatellite motif. Adenovirus-mediated gene therapy may represent a potential therapeutic option for endometriosis in the future. The survival rate in patients with retroperitoneal paraganglioma with lung metastasis is low, and this case represents the longest surviving period reported in the literature.

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Effect of various chemotherapy regimens on survival and cause of death in patients with multiple myeloma (retrospective study) Spinal cord stimulation (SCS) is used for treating intractable neuropathic pain. In order to prevent this severe complication, a surgical alternative has been proposed which consists in delaying the reconstruction until gastric perfusion improves. These changes are most commonly found in two situations: (1) Injuries of the upper cervical spine. In four test reactors, nitrate or nitrite was added (250 mg N-NO(x)(-)L(-1)) during municipal solid waste biodegradation.

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Clinical and morphological outcomes of the aneurysms were assessed, including technical aspects of treatment. Furthermore, the volume of both soft and calcified plaques correlated significantly with WMLL.

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Registry data concur with Sydney criteria, whereby aPL-ITD-positive patients are classified as having antiphospholipid syndrome. To evaluate efficacy and safety of delivery room (DR) sustained lung inflation (SLI) in resuscitation of preterm neonates.

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(3) Eggs and 2 cell stage embryos raised at 5G showed a greater extent of brain and eye apoptosis compared with controls, while those raised at 2G showed no significant difference. Tissue distribution showed that the highest concentration was observed in the lung, followed by heart, liver and kidney.

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The optical absorption coefficient became higher due to the decrease in the center-to-center distance of NDs to enhance wavefunction coupling. To explore and describe the nutrition and health transition in Thailand in relation to social and economic changes, shifts in food consumption patterns and nutritional problems, as well as morbidity and mortality trends. WebQuests: creating engaging, student-centered, constructivist learning activities.

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EBUS-TBNA specimens can be used for molecular analysis such as epidermal growth factor receptor (EGFR), Anaplastic lymphoma kinase (ALK) and V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations when processed properly. Reproductive health services for adolescents in Kabarole district could be strengthened by improving the privacy and confidentiality of services.

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Women presenting for intended home birth in these practices were enrolled in the study from late 1994 to late 1995. Retraction: Atorvastatin Improves Survival in Septic Rats: Effect on Tissue Inflammatory Pathway and on Insulin Signaling. Haemodynamic effects of adrenomedullin in human resistance and capacitance vessels.

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A repeat of the mitral valve replacement was performed, and preoperative CT findings of both the thrombus on the left atrial side and pannus formation on the LV side were confirmed in the operative findings. We show here that this method is sub optimal and increases the performance significantly in only one out of five datasets. We report the case of a 57-year-old patient admitted with foot drop, due to an extraneural ganglion of the upper tibiofibular syndesmosis, compressing the deep branch of the peroneal nerve. Single-file techniques appear to be the effective and efficient method for curved canal preparation. In conclusion, VIP might exert a renoprotective effect by the suppression of oxidative stress.

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To evaluate whether familial resemblance of BP is mediated by body size, the original systolic pressures were adjusted by stepwise multiple regression of age, sex, height, weight and skinfold thickness. Identifying factors likely to influence death is useful in primary care, as this can initiate discussion about end-of-life care. The involved health care providers should have adequate education and training in their respective disciplines and should be networked allowing quick turnaround times.

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Engineering plant metabolism into microbes: from systems biology to synthetic biology. It also indicated enhancement in the production of several polyphenols and also an increase in antioxidant activity in the additive-treated callus. This research demonstrates that MFCs fed with lactic acid can generate a high efficiency of current density, and that the dominant microbes on the anodes are similar to that of inoculated sludge. A semiconductor optical amplifier is grown on an InAsP metamorphic substrate to extend the long wavelength accessibility of the amplifier.

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Interestingly, it was recently demonstrated that DS obtained from skin of the eel Anguilla japonica, which possesses a disaccharide composition very similar to that of electric eel skin DS described here, did not show anticoagulant activity. In another patient, we show that the mean PV changes with sleep and an epileptic seizure. On the third night the volunteers received placebo or haloperidol and spent the whole night awake. Reduced dermis thickness and AGE accumulation in diabetic abdominal skin.

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The correspondence between the development of ventricular tachycardia and sinus pauses is consistent with the hypothesis that ventricular arrhythmias are initiated by early afterdepolarization-induced triggered activity. Yet, toolboxes for navigating and understanding even small gene or protein networks are poorly developed. A comparative study on the immediate effects of electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and a non-meridian point, on menstrual pain and uterine arterial blood flow, in primary dysmenorrhea patients. In the second period all were treated with local diltiazem (DTZ group). Lower doses of rifampin (50 to 100 mug/ml) preferentially inhibit ribosomal RNA synthesis in comparison to that of messenger RNA and transfer RNA.

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This permits reorientation of the tip of the needle into the target and obviates the need for additional passes. Aerobic 12-week training reduces cardiovascular risk factors in overweight teenagers Many tumour cells have elevated rates of glucose uptake but reduced rates of oxidative phosphorylation.

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Predictors of suicide in major depressive disorder: a follow-up of patients seen at a specialist mood disorders unit. Androgens and the social behavior of male and female lizards (Anolis carolinensis). SD and light also led to cellular DNA breakdown, although only light caused ROS production. Bacterial cells also regulate their polarity dynamically to reverse their direction of movement.

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Reported data indicate that good results can be obtained provided that computational strategies, exchange-correlation functionals and basis sets are carefully selected and applied. Automated sample preparation using in-tube solid-phase microextraction and its application -- a review.

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The aim was to develop a new measure (the Cardiff Beliefs Questionnaire, CBQ) to establish the range and prevalence of delusion-like beliefs (DLB) and compare these to other types of beliefs in the general population. Low-molecular-weight heparin (LMWH) is at least as effective as unfractionated heparin (UFH) in the treatment of PE, with a similar risk of bleeding. Four cases are reported which demonstrate the prompt and effective reversal of diazepam-induced delirium and coma by the administration of physostigmine. We evaluated T cell recognition of the complete array of preproinsulin (PPI) peptides with regard to HLA binding affinity and T cell recognition. From these results it was concluded that Type I cells may originate from Type II cells in human lungs as they do in experimental animals.

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Analysis of the proteomes in the cells depleted for hnRNP A1, A2, or A3 has identified a total of 167 differentially expressed proteins in the depleted cells. Despite the focus on power-law models, the analyses and conclusions are extendable to other canonical models, and the issue of parameter identifiability is expected to be a common problem in biochemical system modeling.

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Cerebral blood flow in the newborn infant: comparison of Doppler ultrasound and 133xenon clearance. In this mini review the metabolic pathways in several phytopathogenic fungi and the non-infectious asporogenous yeast Candida boidinii, which involve lipid droplets and peroxisomes, are summarized. Homoeolog-specific retention and use in allotetraploid Arabidopsis suecica depends on parent of origin and network partners. In addition, the construction of such estimating equations routinely requires solving integral equations, hence the computation is often much more intensive compared with ordinary regression models. Type of intractable temporomandibular disorder and treatment protocols.