Trazodona is an FDA-approved antidepressant for treating major depressive disorders. It can be used as part of a combination therapy with other drugs or psychotherapies or used by itself for treating depression. Non FDA-approved use is meant to induce sedation in patients with sleep problems. These patients may or may not have concurrent depression. Because of a lack of sufficient clinical data for justifying its use as a sleep aid, Trazodona is not FDA-approved for sleep disorders. Trazodona is also used off-label for anxiety, Alzheimer disease, substance abuse, bulimia, and fibromyalgia due to its serotonergic receptor antagonism and serotonin reuptake inhibiting effects. Trazodona has also been used for post-traumatic stress disorder (PTSD) if the first-line treatment use of SSRIs does not show efficacy. The dose of 50 mg to 200 mg of Trazodona has been shown to reduce episodes of a nightmare as well as improving sleep habits in studies involving PTSD patients. However, various studies show panic symptoms have been exacerbated in certain cases, which is why SSRIs, instead of Trazodona, are preferred as the first-line treatment for PTSD. In addition, Trazodona has been shown to improve apnea and hypopnea episodes in patients with obstructive sleep apnea (OSA), and the drug does not worsen hypoxemic episodes. It raises the respiratory threshold, lowering risk of respiratory instability.
Other names for this medication:
Trazodone,
Desyrel,
Azona,
Donaren,
Mesyrel,
Nestrolan,
Oleptro,
Reslin,
Trant,
Trazodon,
Trazodona,
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