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Propecia is part of a class of drugs known as 5-alpha-reductase inhibitors (5-ARIs). It is approved only for use in men because it can cause ambiguous genitalia in developing male fetuses. Drugs in the 5-ARI class include Propecia, marketed under the brand names Propecia (5 mg) and Propecia (1 mg); and dutasteride, marketed as Avodart and Jalyn (in combination with tamsulosin). Propecia, Avodart, and Jalyn are approved to treat symptoms of an enlarged prostate gland, or benign prostatic hyperplasia (BPH). Propecia and Avodart are also approved to reduce the risk of urinary retention or the need for BPH-related surgery. Propecia is the only 5-ARI approved to treat male-pattern hair loss. Dutasteride is not formally approved for treating hair loss, but it may be used off-label for this purpose.

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Recent evidence suggests that the variability of drug effects may depend on precise intrinsic properties of dynamic networks involving the drug and its binding site. Prevalence of Hepatitis B Antigen/antibody in Patients of Syphilis. The specific capacity (Cm) of bilayers made from monoolein monolayers showed a negligible voltage dependence, whereas the Cm increased significantly at a voltage of 150 mV in the case of Mueller-Rudin-type monoolein films with n-decane as a solvent. ReactionPredictor: prediction of complex chemical reactions at the mechanistic level using machine learning.

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Effect of signal to noise ratio on the speech perception ability of older adults. An Analysis of the Correlation between Alopecia and Chief Complaints. The heterodimers differ by the nature of the spacer structure, for which-in the second compound-a PEG/two-amide spacer was introduced. Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19. The present SFG and AFM observations revealed similar temperature dependent profiles.

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Prostaglandins and drug induced agranulocytosis, aplastic anaemia and leukemia. Controllable Molecule Transport and Release by a Restorable Surface-tethered DNA nanodevice.

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Intravoxel Incoherent Motion Imaging in Small Vessel Disease: Microstructural Integrity and Microvascular Perfusion Related to Cognition. Therefore, all the procedures involving medical treatment, surgical operations, assisting reproductive technologies, treatment of mentally disabled persons, and treatment of children should have proper consent in terms of age, mental capacity, free will, and full disclosure.

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These patients had more favorable pathologic findings, including less deep invasion, better differentiation, more intestinal type, and less frequent lymphovascular/perineural invasion than patients with solitary EGCs. Empirical data on means of preventing or remedying diabetes in Third-World countries Pre- and postoperative data, including the frequency of pneumonia treatment, the frequency of sputum suctioning, the respiratory condition, the nutrition method, and the outcome after LTS were assessed.

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These outcomes contrasted with the heightened controversy generated by the recommendation against PSA screening and other early detection strategies. Statistical analysis demonstrated the five of the six criteria (preponderant texture, preponderant outline, fracture relationship to least resistance path, plastic response and the presence of hinging) subjected to statistical analysis bore statistical significance in distinguishing between perimortem trauma and postmortem damage when using 3D CT images.

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Four experimental conditions (i.e., normal, with an imposed pace, dual-task, or with the neck bent) were tested. Activity-based anorexia is associated with reduced hippocampal cell proliferation in adolescent female rats.

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The action of caffeine post-treatment after UV exposure in three strains of diploid yeast has been studied. The purpose of this study was to assess individual mechanisms of effort intolerance in patients with heart failure with preserved ejection fraction (HFpEF), heart failure with reduced ejection fraction (HFrEF), or normal cardiac function using combined echocardiography and cardiopulmonary stress testing. Nerve injury triggers up-regulation of p75NTR in Schwann cells (SC) but not in central glia.

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The observed Toxoplasma-associated differences were always larger in RhD-negative than in RhD-positive subjects. Pertussis and measles infection as well as vaccination have been suspected as possible mediating factors of allergic disease in childhood. Purification and some properties of a novel dsRNA degrading nuclease bound to rye germ ribosomes. Surgery on patients with malignant obstructive jaundice carries increased risks of postoperative morbidity and mortality. However, these patients were super-selected, which does not reflect a clinical real-world situation.

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Our results suggest that our technique may enhance both success rate and efficacy in lowering IOP. We show that PfPuf1 was expressed in all gametocyte stages and at higher levels in female gametocytes. In our study, obese individuals had intestinal insulin resistance regardless of their glycaemic status. Paris Saponin II suppresses the growth of human ovarian cancer xenografts via modulating VEGF-mediated angiogenesis and tumor cell migration.

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The modeling studies showed that the distal pocket of the heme consisting of the Y96, T101, F87 and L244 residues could be suitably mutated to change the substrate specificity of the enzyme. To understand the differences in the organization of mitochondrial genomes of the very closely related Aspergillus niger and Aspergillus tubingensis species, we determined the complete genome sequence of the 1a mtDNA type of A. When protein-based biomineralization meets hydrothermal synthesis: the nanostructures of the as-prepared materials are independent of the protein types. For each child in our study, we calculated inverse distance weighted (IDW) oil and gas well counts within a 16.1-kilometer radius of residence at cancer diagnosis for each year in a 10 year latency period to estimate density of oil and gas development. The results indicated that the nanostructured DLC-Cu thin film coating reduced excessive thermal injury and tissue adherence effect in the liver.

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Increased density causes reduced offspring size, decreased fat storage by adult females, and increased adult mortality. The patient died despite the intensive supportive treatments that were performed. These improvements also suggest advances in disease surveillance, transparency in reporting, and regional collaboration and cooperation. Numerous other metabolic disorders can be sited in which significant liver involvement occurs. The study evaluates the levels of alexithymia in nine adult male subjects with AS.

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The results obtained with the use of a clinical pathway for patients undergoing transurethral resection for benign hyperplasia of the prostate (BPH) are presented. In twelve women, in whom labor was induced by oxytocin infusion, intra-uterine pressure (IUP) was recorded by micro-transducers, and simultaneously the diameter of the uterine cavity was estimated by means of ultrasound. These results show that iNs retain important aging-related signatures, thus allowing modeling of the aging process in vitro, and they identify impaired NCC as an important factor in human aging. EVALUATION, FEEDBACK AND REMEDIATION IN ANESTHESIOLOGY RESIDENCY TRAINING: A SURVEY OF 124 UNITED STATES PROGRAMS. This prospective study involved a convenience sample of 30 healthy patients, ranging from 2 to 5 years of age, who were scheduled to undergo sedation in the dental clinic for operative procedures.

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Results showed significant differences among the geographical categories, with diabetic individuals in the most sparsely populated communities reporting fewer physician office visits and more home health visits than their urban counterparts. The rationale of patients with early-stage papillary thyroid cancer for accepting or rejecting radioactive iodine remnant ablation.

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Mathematically generated phantoms (one with curved fibers and the other with crossing fibers) at wide ranges of signal-to-noise ratio (SNR), and human brain images obtained in vivo were used to test the performance of the adaptive stepping algorithm. The inner ear contains a single auditory endorgan, the amphibian papilla, somewhat similar to this organ in anurans. These findings indicate WMSA is an important pathological component of AD development. This investigation was an initial attempt to explore psychological factors that might help or hinder the effect of exposure in vivo for patients with musculoskeletal pain and pain-related fear. There was an increasing trend of delinquent behavior with the growth rate slowing down over the high school years.

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Impaired olfaction and other prodromal features in the Parkinson At-Risk Syndrome Study. Purchasing cattle into recipient herds poses a high biosecurity risk due to the possibility of introducing disease. Results suggest ongoing development of social cognition across adolescence, independent of individual differences in more basic cognitive abilities.

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The purposes of this study were to (1) assess receptiveness of families to violence prevention interventions initiated after an assault injury and (2) assess the effectiveness of a case management program on increasing service utilization and reducing risk factors for reinjury among assault-injured youth presenting to the emergency department. In addition, we determined the cell-cycle dependence of the phosphorylation of these sites by using stable isotope labeling and MS(2) analysis.

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Determination of cardiac output by transcutaneous continuous-wave ultrasonic Doppler computer. Inflammation and reactive oxygen species in cardiovascular disease. External volume expansion applied to mouse integument induces highly proliferative and vascularized subcutaneous tissue. Linusitamarin, a new phenylpropanoid glucoside from Linum usitatissimum.

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Friendship quality in adolescents with and without an intellectual disability. Trypanocidal effect of isometamidium chloride hydrochlorate on Trypanosoma evansi and treatment attempt of trypanosomiasis in dromedary Radioimmunotherapy with radiolabeled monoclonal antibodies is increasingly effective for hematopoietic tumors, with a number of investigators reporting persistent major responses.

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The overexpression of miR-19b was significantly correlated with better disease-free and overall survival in patients with HCC presenting with vascular invasion or multifocal disease after curative surgery. Findings in common with previous studies were an association of poverty with left cortical metabolic activity in prefrontal and superior parietal areas, reality distortion with left temporal activity, and disorganization with left inferior parietal lobule.

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Does GH replacement therapy in adult GH-deficient patients result in recurrence or increase in size of pituitary tumours? Understanding the status and developmental prospects of this area around the world is important to determine research priorities, and to evaluate and direct progress. In African-American women, OCP use is associated with an increase in markers of cardiovascular risk manifested by increased insulin resistance, glucose intolerance, and elevated TGs. To investigate whether OSA is a risk factor for cardiovascular death and to assess whether continuous positive airway pressure (CPAP) treatment is associated with a change in risk in the elderly. This suggests that genetically similar strains can infect a range of different hosts.

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phagocytophilum studies, mice were immunized with the recombinant subolesin protein, infected with the pathogen and then infested with larval Ixodes scapularis. We adopted a principal component analysis (PCA) on the normalized evolutionary distances in order to reveal any patterns in the evolutionary signals contained within the various CGFs. MALDI-TOF MS appears as a powerful technique for the analysis of apoC-III glycoforms for potential routine screening of COG- and ATP6V0A2-CDGs. The RGWG of mid pregnancy was not significantly associated with any adverse pregnancy outcomes. Chronic sleep deprivation is a common occurrence in modern society and has been observed in a number of chronic inflammatory conditions, such as systemic lupus erythematosus (SLE).

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Extrusion index and medial offset distance had lower correlations with ICCs of 0.66 (0.46-0.79) and 0.46 (0.21-0.65), respectively. 2-kilobase mRNA and find that it is highly expressed in HUT-102 cells. Our approach is, thus, a fast and simple application that proved to be efficient and powerful when applied to mitochondrial genomes.

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To describe our experience with four cases of severe pelvic dislocation associated with difficult parturition. The strength of the muscle tendon unit in a child makes tendon injuries extremely unusual as compared to apophyseal avulsions. Chromosomal characterization of armored catfish Harttia longipinna (Siluriformes, Loricariidae): first report of B chromosomes in the genus. MSI analysis was performed by conventional polymerase chain reaction using fluorescent-labeled primers and automated analysis. Soluble factor(s) produced by adult bone marrow stroma inhibit in vitro proliferation and differentiation of fetal liver BFU-E by inducing apoptosis.

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This paper presents initial results using a vibrotactile acuity test for the objective and quantitative diagnosis of acute mTBI suspects. When compared with healthy controls, the microbial profile of subgingival plaque from periodontitis was found to contain known periodontal pathogens with a different prevalence to that described in earlier studies. Since these studies often comprise the genotypes of hundreds of thousands of SNPs, methods are required that stemetil drug prochlorperazine can cope with the corresponding multiple testing problem.

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