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The blockage of VDAC by G3139, a proapoptotic phosphorothioate oligonucleotide, provides strong evidence for the role of VDAC in the initiation of apoptosis. An unusual congenital facial anomaly: erectile proboscis-like structure. Nonetheless, there was modest evidence for the efficacy of mind-body modalities during pregnancy. Aptamer-based fluorescence sensor for rapid detection of potassium ions in urine.

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To solve these problems this paper proposes a fast and automatic center of rotation search method making use of parallel programming in graphics processing units (GPUs). Clinical and urodynamic evaluation of 25 patients after long term follow-up. The use of diffractive beam-shaping elements in hybrid or monolithic microsystems is investigated. The findings could help to tailor interventions to optimally meet the specific needs of overweight children with emotional and behavioral problems. The data extraction method featured here was developed specifically to accommodate mixed-methods mixed research synthesis studies conducted in nursing and other health sciences, but reviewers might find it useful in other kinds of research synthesis studies.

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Ebola viruses are not pathogenic but can be adapted to replicate and cause disease in rodents. Emergency pneumonectomy: a life-saving measure for severe recurrent hemoptysis in tuberculosis cavitary lesion. Taken in conjunction, these properties can provide innovative drugs. A gene (gckA) responsible for the activity of glycerate kinase has been identified within a chromosomal fragment of the serine cycle methylotroph Methylobacterium extorquens AM1.

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In the present study the impact on the gastrointestinal microflora of peroral administration of penicillin, bacampicillin, clindamycin, erythromycin, doxycycline, and tinidazole was investigated. This paper describes the development of an interactive, theory-based website (Sexunzipped) aimed at increasing safe sexual behavior of young people, as well as an outline of the evaluation protocol. Results indicated that van der Waals forces were the leading force, while electrostatic interactions also played an important role in nonspecific interactions. Changes in Characteristics and Treatment Patterns of Patients with Newly Diagnosed Type 2 Diabetes in a Large United States Integrated Health System between 2008 and 2013.

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Injuries to the small and large intestine from blunt trauma represent a defined clinical entity, often not easy to correctly diagnose in emergency but extremely important for the therapeutic assessment of patients. Biophysical regulation of carbon fluxes over an alpine meadow ecosystem in the eastern Tibetan Plateau. A novel assay for the distribution of pyrithione biocides in bacterial cells.

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Oral anticoagulation with vitamin k antagonists (VKAs) requires regular testing and dose adjustment. The aim of this study was to retrospectively evaluate the clinical survival rate of Astra Tech implants in the maxillary molar region performed with sinus lift and bone graft.

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At the end of treatment, participants who no longer met diagnostic criteria for PTSD had greater improvements in all domains of work-related quality of life than participants who still had PTSD. Interestingly, both OB volumes were below the tenth percentile of the general population which seems to be difficult to explain by rapid, adaptive changes in the OB volume.

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First-order transition in a percolation model with nucleation and preferential growth. During 1965-1967, an International Collaborative Study with similar objectives found a striking positive relationship between age at first birth and breast cancer risk. This paper investigates whether such adaptation at a local scale affected health patterns and altered the dietary habits of populations that otherwise shared a common cultural and biological origin.

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Some aspects of classification and treatment strategy of iatrogenic bile duct injury The pattern of lung function abnormalities in cotton textile workers. The relationship of RLIP76 expression with clinicopathological features and prognosis of the patients was analyzed.

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Recently, this diagnosis was confirmed by molecular genetic analysis that demonstrated the presence of a heterozygous constitutive activating mutation of the luteinizing hormone/chorionic gonadotropin receptor. To estimate dosimetric uncertainty, deformable registration was performed on their daily CBCTs to generate 4DCT equivalent scans for each fraction and to map recomputed dose to a common frame. Electrocardiographic signs of right ventricular strain are strongly related to elevated cardiac biomarkers and echocardiographic signs of right ventricular overload.

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The fixed, isolated oligomer was deposited on electron microscopy grids, dehydrated, and then critical point-dried before shadow-coating with carbon/platinum alloy at a fixed angle. Additionally, strategies to improve access of the school children population to dental services must be elaborated. In both humans and animals, cerebral ischemia damages the nerve cells in vulnerable regions of the brain, viz., hippocampus, cerebral cortex, cerebellum, and hypothalamus. The proposed algorithm takes into consideration not only simulation of simple cortical cells in the receptive field of humans but also the texture-color feature global spectrum contrast of an image. However, as far as we know, no attempt has been made to adjust for the variation due to DNA copy number changes in RNA-seq data normalization.

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Macrophage inflammatory protein-3alpha (MIP-3alpha or CCL20) is an intriguing molecule in cancer immunotherapy, but MIP-3alpha expression and signalling are not well understood in oral cancer cells. The lamellae, each 30-45 nm in thickness, are piled one on top one another at intervals of 10-20 nm. Slight enzymatic breakdown of PGs, or altered synthesis due to cellular responses to either the injury directly or to synovial inflammation, seems necessary to explain such changes in the absence of cartilage erosion.

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Induction chemotherapy followed by radiotherapy in patients with cervical lymph node metastases from unknown primary carcinoma. In root coverage, these technologies were able to improve new attachment, although none has shown complete regeneration.

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Regression analyses were computed for predicting length of care and costs after the first year. The free anterolateral thigh flap was the ideal soft tissue flap in the intraoral defects reconstruction. Racemic indolines including a variety of structural motifs such as C-2 and C-3 substitutions (alkyl or aryl), cis/trans relative stereochemistry and functionalization of the aromatic ring (fluoro, methyl or methoxy groups) have been efficiently prepared through Fischer indolization and subsequent diastereoselective reduction of the unprotected indoles. Their robust associations with re-experiencing symptoms affirm that MRS indices of hippocampus neuron integrity and glutamate metabolism may reflect biomarkers of clinically significant disease variation in PTSD. General physical examination was unremarkable and the abdomen was soft, with no palpable organomegaly.

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Cutting the entire collateral medial ligament caused only slight valgus instability, even when the knee was flexed. Overall, image-guided lung tumor ablation is a minimally invasive procedure that has an acceptable safety profile and less impact on lung function.

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Averaged divisional frequency of each type was calculated in the range below 1 Hz in which the main change between the values with eyes open and those with eyes closed appeared as the frequency shift. Using interactive video technology in nursing education: a pilot study. Measuring and analyzing complex recombination-based systems constitute a major barrier to understanding the mechanisms used to generate diversity.

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Genetic studies were carried out on the 18 patients selected that were included for statistical analysis. Relation between distal motor latency delay and sensory action potential absence of the median nerve in carpal tunnel syndrome.

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Experimental carbon dioxide poisoning in a cat with ligation of the unilateral common carotid artery An overview of techniques for dealing with large numbers of independent variables in epidemiologic studies. Information about baseline characteristics was based on questionnaire responses and medical examination. Higher fruit and vegetable intakes may have positive effects on bone mineral status in both younger and older age groups, especially at the spine and femoral neck. The possibility of mosaicism should be considered in subjects with RTH without apparent mutations in the TRbeta gene.

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These applications are illustrated by reviewing the use of plasma chitotriosidase in the clinical management of patients with Gaucher disease, the most common LSD. A generalised theoretical model was developed to explore the conditions, such as volume flow rates and tubular lengths etc., for which a near-full electrolysis may be achieved. Development of a highly efficient protein-secreting system in recombinant Lactobacillus casei. As an abundant ingredient in Huangqin, wogonoside is a flavonoid glycoside.

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A transfer matrix method is developed and applied to find accurate values of the density and degeneracy of the maximum independent set on lattices of limited width but large length. These data suggest the possibility that ALA may be useful for the prevention of neointimal hyperplasia after angioplasty, by inhibiting the NF-kappaB/MMP-9 pathway, especially with hyperglycemia. We investigated the factors contributing to LA enlargement in patients with normal LV systolic function, addressing its gender difference. The C-terminal protein domain is released without additional amino acids, whereas the N-terminal protein domain retains the short C-terminal end of Ub. Let us try to do the same by preventing the development of violent behaviors.

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Chronic and inescapable trauma is implicated in the stress-induced analgesia (SIA) response. Fifteen minutes after creation of pneumoperitoneum, they were randomized to receive either VCV (Group V) or PCV (Group P). Immunohistochemical expression of uPA, PAI-1, cathepsin D and apoptotic cells in ductal carcinoma in situ of the breast. Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. False tuberculosis outbreak caused by specimen contamination in a micro-bacteriology laboratory: confirmation by molecular techniques

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In obese rats switched to chow, intake was inadequate for normal pup growth. A simple operation method was described for removing the olfactory bulbs of small rodents.

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Arabidopsis cpFtsY mutants exhibit pleiotropic defects including an inability to increase iron deficiency-inducible root Fe(III) chelate reductase activity. Mechanism of action may be through metal chelation or activation of endogenous antioxidant enzymes, because the extract did not show hydroxyl and super oxide anion scavenging property. Radiobiolical investigations with fast neutrons using the cartilage clone system. To compare the pharmacodynamics of two commonly recommended doses of rocuronium bromide (0.7 mg/kg and 0.9 mg/kg) and succinylcholine (1.5 mg/kg) when used for rapid-sequence intubation. In addition to these physiological roles, an important role for polarity proteins in cancer progression has also been uncovered, with loss of polarity and tissue architecture being strongly correlated with metastatic disease.

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The population, which has 90 percent of the cells in the G1 phase of the division cycle, was not static and exhibited a low level of mitotic activity with prolonged interdivision times. These plasma cells, characteristically located in niches among hepatocytes, in close contact with collagen fibrils, have been hypothesised to exert a role in fibrogenesis stimulation, and particularly in collagen synthesis, possibly through secretion of lymphokines. Herein, we report a rare case of an isolated IAA accompanied by type B aortic dissection and extensive collateral arteries detected by multidetector computed tomography in a 38-year-old man. In distributed electronic systems, such as antenna arrays and multi-core processors, a common time reference is key to coordinate signal transmission and processing.

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Towards elucidation of the toxic mechanism of copper on the model green alga Chlamydomonas reinhardtii. We analyzed the evoked electroencephalography (EEG) responses and applied distributed electrical source imaging techniques to estimate activity differences between conditions and groups throughout the brain. Due to this, policy makers need to develop novel strategies or resort to a combination of multiple intervention strategies to control the spread of the disease.

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The age-related changes were considered to be of greater significance than those related to sex and growth rate when interpreting serum LDH levels in lambs. Protein pyrophosphorylation is emerging as a new post-translational modification, yet its role in cellular signaling remains poorly characterized.

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The effects of baclofen, a gamma-aminobutyric acid derivative, on conditioned avoidance behaviour and on the turning produced by unilateral 6-OHDA lesions of the s. The purpose of our report was to ascertain the 15-year survival and analyze failures. Healthy adults were asked to react to sudden onset peripheral targets while demand on non-spatial attention was manipulated via a central task. Fifty serum samples from 43 consecutive patients referred for suspected infectious mononucleosis and positive for VCA IgG-, VCA IgM- and EBNA-1-antibodies by EIA, were tested for IgG-antibody avidity with an EBV IgG immunoblot.

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Ordinary clinical manifestation of the patient with bilateral vocal fold paralysis is inability of abducting the cords with a result of narrowing the glottic space, causing inspiratory stridor and mild dysphonia. The myelin loss along the periphery of the lesion was erroneously interpreted as TD during the histopathological examination. Dynamics of acid and alkaline secretion of the stomach as a function of the period and phase of the secretory cycle in peptic ulcer

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Taking all this together, it can be concluded that Fan is an effective anti-proliferative agent that modulates cell growth regulators in prostate cancer cells. Participants low in SA made equal use of all strategies, while for those high in SA reappraisal and acceptance were more efficient than pondering. In this study, we investigated the effects of vitamin E (alpha-tocopherol and delta-tocopherol) on the osteoblasts isolated from rat calvariae. First, the GM-CSF whole cell vaccine was evaluated against subcutaneously transplanted esophageal tumor cells. niobe, Crocidura sp.), collected in the DR Congo is also described.

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Root surface treatment using diode laser in delayed tooth replantation: radiographic and histomorphometric analyses in rats. The following systems were used: Ca-alginate granules (AG) prepared by various methods, porous carbonate cores with multilayer polyelectrolyte coating as well as the new two-level DS (Ca-AG containing carbonate cores loaded with proteins). Intraobserver agreement was calculated for 11 replicate measurements for each observer. Isradipine was more potent in blocking growth factor-induced cell growth than the other calcium antagonists studied. Treatment is generally supportive, because there are no reversal agents for inhalant intoxication.

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This article presents four typical cases in which fiber-reinforced fixed partial dentures seemed to be the preferable treatment modality. In particular, the relative standard deviation (RSD) of the TAMSD can be utilized to study the long-time relaxation behavior.

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A detailed analysis of the transferability, the within- and between laboratory reproducibility and the predictivity is presented. Key roles of EMT for adaptive resistance to MEK inhibitor in KRAS mutant lung cancer. Whether patients with preexisting liver disease are at increased risk when receiving thalidomide remains to be seen. Our results may explain why protein folding is efficient at constant temperature. RA patients have a high risk of fracture, and the adoption of a risk-scoring system should be considered.

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Expression QTL modules as functional components underlying higher-order phenotypes. We conducted semistructured interviews with parents of 25 pediatric outpatients with CMA test results indicating either a pathogenic alteration or a variant of unknown significance (VUS). The material was produced by reacting B2O3 with nanoporous carbon spheres under nitrogen at ca. Suggested mechanisms behind fetal growth are often linked to the feto-maternal circulation, including the development of placenta and umbilical cord. Two reviewers independently assessed the identified studies against the eligibility criteria and extracted relevant information.

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A cost-effectiveness analysis (CEA) was estimated as the incremental cost to reduce staff radiation exposure. Superiority of K-edge XANES over LIII-edge XANES in the speciation of iodine in natural soils. It could be used as an adjunctive agent to increase efficacy of radioiodine therapy if combined with a strategy to increase NIS protein trafficking to cell membrane. In order to investigate the influence of these changes on motor function, the relation between local temperature and nervous conduction velocity in a peripheral motor nerve (n. There is evidence that minicolumns may be smaller in extant humans within selected populations, and the implications of this are briefly considered.

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To model the progression of 3 functional outcome measures from patients with incomplete spinal cord injury (SCI) receiving standardized locomotor training. Group B Streptococcus (GBS) is a known causative pathogen of neonatal sepsis, but the epidemiology in non-pregnant adults is less studied.